[Antiviral agents in influenza--current recommendations. Anti-influenza agents are not a substitution for but a complement to vaccination].

Lakartidningen

Infektionskliniken, Akademiska sjukhuset, avdelningen for klinik och preklinik 1, Läkemedelsverket, Uppsala.

Published: January 2006

This article summarizes a Swedish consensus guidance document on the use of antiviral drugs in the management of influenza. Vaccination remains the cornerstone for influenza prophylaxis. Treatment with neuraminidase inhibitors is recommended for high-risk groups and individuals hospitalised with influenza. Chemoprophylaxis is targeted at high-risk groups and should be considered on a case by case basis depending on the circumstances. Unvaccinated at-risk patients or seasonal vaccine strain mismatch were identified as potential indications for antiviral prophylaxis. Oseltamivir prophylaxis can otherwise be considered for influenza in a household including an at-risk individual and in outbreaks in hospitals and nursing homes. The use of antivirals in a pandemic situation is also discussed.

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