Pravastatin-induced lichenoid drug eruption.

Australas J Dermatol

Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

Published: February 2006

SUMMARY A 64-year-old woman presented with diffuse and numerous pigmented macules on her face and upper back. Histopathological examination of a skin punch biopsy of the rash showed a lichenoid dermatitis. The most likely offending drug was pravastatin. Cessation of pravastatin resulted in gradual fading of the pigmentation. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors have previously been reported to cause lichenoid drug eruptions.

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http://dx.doi.org/10.1111/j.1440-0960.2006.00225.xDOI Listing

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