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Diffuse large cell non-Hodgkin's lymphoma, CD30+, T-cell phenotype. | LitMetric

AI Article Synopsis

  • A 63-year-old Chinese man developed an eczematous dermatitis that later evolved into a nodular skin eruption.
  • Histopathological analysis revealed a mixture of lymphocytes, macrophages, eosinophils, and reactive lymphoid follicles in the skin.
  • He was diagnosed with CD30+ cutaneous T-cell lymphoma and is currently being staged for treatment, which may include surgery, radiation, or chemotherapy.

Article Abstract

A 63-year-old Chinese man presented with an eczematous dermatitis that progressed into a multifocal nodular eruption. Histopathologic examination demonstrated a nodular and diffuse infiltrate in the reticular dermis, which was composed of lymphocytes, macrophages with granulomatous inflammation, and numerous eosinophils. Reactive lymphoid follicles with germinal centers also were present. Immunohistochemistry showed CD30 and LCA. ALK-1 and CD20 were negative. A diagnosis of CD30+ cutaneous T-cell lymphoma was made, and the patient is currently undergoing staging of his disease. Treatment options include excision of nodules, radiation therapy, and systemic chemotherapy.

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