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Heterogeneity of treatment effect: the case for individualising oxygen therapy in critically ill patients.
Crit Care
January 2025
Perioperative and Critical Care Theme, NIHR Southampton Biomedical Research Centre, University Hospital Southampton/University of Southampton, Southampton, UK.
Oxygen therapy is ubiquitous in critical illness but oxygenation targets to guide therapy remain controversial despite several large randomised controlled trials (RCTs). Findings from RCTs evaluating different approaches to oxygen therapy in critical illness present a confused picture for several reasons. Differences in both oxygen target measures (e.
View Article and Find Full Text PDFSurgical management of lateral epicondylitis: a scoping review of published literature.
JSES Rev Rep Tech
February 2025
Rowley Bristow Orthopaedic Unit, Chertsey, UK.
Background: Surgical intervention for lateral epicondylitis remains a controversial topic, with its purpose being debated. Recent guidelines have concluded no benefit from surgery when compared to conservative management.
Methods: An electronic database search of Ovid Medline via PubMed, EMBASE, and the Web of Science was performed to understand the published literature further.
The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis.
Front Endocrinol (Lausanne)
January 2025
Department of Traditional Chinese Medicine, Zigong First People's Hospital, Zigong, Sichuan, China.
Background: The effects of resveratrol supplementation on inflammation and oxidative stress in patients with type 2 diabetes mellitus (T2DM) were controversial. A meta-analysis was performed to assess the changes in levels of inflammation and oxidative stress in patients with T2DM.
Methods: Relevant literatures before November 6, 2024 were screened through Web of Science,Embase,the Cochrane Library and other sources (ClinicalTrials, ProQuest Dissertations and Theses).
From impact metrics and open science to communicating research: Journalists' awareness of academic controversies.
PLoS One
January 2025
College of Medicine, University of Illinois Chicago, Chicago, IL, United States of America.
This study sheds light on how journalists respond to evolving debates within academia around topics including research integrity, improper use of metrics to measure research quality and impact, and the risks and benefits of the open science movement. It does so through a codebook thematic analysis of semi-structured interviews with 19 health and science journalists from the Global North. We find that journalists' perceptions of these academic controversies vary widely, with some displaying a highly critical and nuanced understanding and others presenting a more limited awareness.
View Article and Find Full Text PDFMedical care and initial health status of French children returnees from Jihadist Group Operation Areas: a cross-sectional study from 2017 to 2020 in one referral French hospital.
Travel Med Infect Dis
January 2025
Pediatrics and emergency department, Hospital Jean VERDIER, Avenue du 14 juillet, Bondy, FRANCE.
Introduction: The return of foreign fighters's children whose parents joined the so called « islamic state » in the Iraq-Syrian area, had been a very controversial topic. Since 2017, a national procedure in France has been designed to coordinate their care, including a systematic pediatric medical assessment.
Methods: The aim of this cross-sectional study was to assess the prevalence rate of diseases diagnosed at their arrival in France.
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