Antispasmodic activity-guided fractionation together with chemical analysis led to the isolation of one novel delta-lactone named oedogonolide from Oedogonium capillare. Identification was based on spectroscopic methods. The oedogonolide produces a significant antispasmodic effect on the contractions of the rat ileum induced by acetylcholine, histamine and barium chloride.
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delta-Lactone from Oedogonium capillare and their effects on rat ileum.
Nat Prod Res
March 2006
Laboratorio de Investigación de Productos Naturales, Escuela Superior de Ingeniería Química e Industias extractivas IPN, Punto fijo 16, col. Torres Lindavista cp 07708, México D.F., México.
Antispasmodic activity-guided fractionation together with chemical analysis led to the isolation of one novel delta-lactone named oedogonolide from Oedogonium capillare. Identification was based on spectroscopic methods. The oedogonolide produces a significant antispasmodic effect on the contractions of the rat ileum induced by acetylcholine, histamine and barium chloride.
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