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Cost Effectiveness of Colorectal Cancer Screening Strategies in Middle- and High-Income Countries: A Systematic Review.
J Gastroenterol Hepatol
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background And Aim: Colorectal cancer (CRC) is a significant global health burden, and screening can greatly reduce CRC incidence and mortality. Previous studies investigated the economic effects of CRC screening. We performed a systematic review to provide the cost-effectiveness of CRC screening strategies across countries with different income levels.
View Article and Find Full Text PDFScreen-Printing vs Additive Manufacturing Approaches: Recent Aspects and Trends Involving the Fabrication of Electrochemical Sensors.
Anal Chem
January 2025
Department of Nature Sciences, Mathematics and Education, Federal University of São Carlos, 13600-970 Araras, São Paulo, Brazil.
A few decades ago, the technological boom revolutionized access to information, ushering in a new era of research possibilities. Electrochemical devices have recently emerged as a key scientific advancement utilizing electrochemistry principles to detect various chemical species. These versatile electrodes find applications in diverse fields, such as healthcare diagnostics and environmental monitoring.
View Article and Find Full Text PDFEffectiveness of Occlusal Splints in the Management of Temporomandibular Disorders: Comparisons of Treatment Approaches and Digital Versus Conventional Fabrication Techniques.
Cureus
January 2025
College of Dentistry, King Saud University, Riyadh, SAU.
This research explores the types and effectiveness of occlusal splints in managing temporomandibular disorders (TMDs). TMDs encompass a range of musculoskeletal and neuromuscular conditions affecting the jaw, causing pain, limited movement, and discomfort. Occlusal splints, also known as bite guards, are commonly used in dentistry to alleviate TMD symptoms by relaxing jaw muscles, preventing joint trauma, and protecting teeth.
View Article and Find Full Text PDFRapid and automated interpretation of CRISPR-Cas13-based lateral flow assay test results using machine learning.
Sens Diagn
December 2024
Department of Bioengineering, Rice University Houston TX 77030 USA
CRISPR-Cas-based lateral flow assays (LFAs) have emerged as a promising diagnostic tool for ultrasensitive detection of nucleic acids, offering improved speed, simplicity and cost-effectiveness compared to polymerase chain reaction (PCR)-based assays. However, visual interpretation of CRISPR-Cas-based LFA test results is prone to human error, potentially leading to false-positive or false-negative outcomes when analyzing test/control lines. To address this limitation, we have developed two neural network models: one based on a fully convolutional neural network and the other on a lightweight mobile-optimized neural network for automated interpretation of CRISPR-Cas-based LFA test results.
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