The aim of the present work was to study the reactive changes in avian (chicken) hepatic microcirculatory bed and epithelium following a single exposure to hyperthermic conditions at different stages of ontogenesis. Application of morphometric methods resulted in a demonstration of a unidirectional response of hepatic acinus vascular bed in embryonic period and after hatching of the birds, as well as differently directed effects of the mechanisms of cellular reproduction. In both experimental groups, heat shock results in the destructive changes in hepatic epithelium.

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