Objective: To investigate the expressions of serum TIgE and SIgE in patients with noninvasive fungal sinusitis and their significance.

Method: Twenty-three cases of noninvasive fungal sinusitis were analysis retrospectively. The expressions of serum TIgE and SIgE were detected by the Unicap system. The expressions of serum TIgE and SIgE in the subtypes of noninvasive fungal sinusitis were analysis statistically.

Result: Positive expressions of serum TIgE and SIgE in 23 cases were 10 cases (43%) and 7 cases (30%) respectively. In 14 cases of fungal ball, the positive expressions of serum TIgE and SIgE were 2 cases (14%) and 1 case (7%) respectively. In 9 cases of allergic fungal sinusitis,the positive expressions were 8 cases (89%) and 6 cases (67%) respectively. The different expressions of serum TIgE and SIgE between the two subtypes of noninvasive fungal sinusitis were statistically significant (P < 0.05).

Conclusion: In noninvasive fungal sinusitis, the detection of the expressions of serum TIgE and SIgE is an available way to distinguish the type of allergic fungal sinusitis from the type of fungal ball,and so it would be helpful to guide the treatment.

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