Cytotoxicity-guided fractionation of the stems of Helicteres hirsuta, of Indonesian origin, led to the isolation and identification of six lignans, namely, (+/-)-pinoresinol, (+/-)-medioresinol, (+/-)-syringaresinol, (-)-boehmenan, (-)-boehmenan H and (+/-)-trans-dihydrodiconiferyl alcohol. Of these isolates, (+/-)-pinoresinol exhibited potent cytotoxic effects when evaluated against a small panel of cancer cell lines.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ptr.1806 | DOI Listing |
Publication Analysis
Top Keywords
stems helicteres
8
helicteres hirsuta
8
cytotoxic lignans
4
lignans stems
4
hirsuta collected
4
collected indonesia
4
indonesia cytotoxicity-guided
4
cytotoxicity-guided fractionation
4
fractionation stems
4
hirsuta indonesian
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!