Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1352284 | PMC |
| http://dx.doi.org/10.1128/AEM.72.1.953-955.2006 | DOI Listing |
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HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins.
Appl Environ Microbiol
January 2006
School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom.
Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.
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