This paper examines, from a thorough review of the literature, the negative effects of haste (excessive eagerness to act) in clinical cardiology such as early discharge from the hospital, premature timing in surgery, too much enthusiasm for new technologies, exaggerated emphasis on tests or pharmacological measures for prevention and inaccurate transfer of results of trials to daily clinical practice. Avoiding haste allows doctors and nurses to provide their patients with the best traditional diagnostic and therapeutic procedures, to guide them wisely to the new ones and to have time enough for an accurate evaluation of all their personal, familial and social problems.
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http://dx.doi.org/10.2143/AC.60.6.2004927 | DOI Listing |
JAAPA
October 2024
James F. Cawley is a professor and scholar-in-residence in the Physician Assistant Leadership and Learning Academy at the University of Maryland, Baltimore, a professor in the PA program at Florida State University in Tallahassee, and a professor emeritus at George Washington University in Washington, D.C. The author has disclosed no potential conflicts of interest, financial or otherwise.
During the 1980s and 1990s, international medical graduates (IMGs) sought legal and educational measures aimed at obtaining licensure as physician associates/assistants (PAs). Proponents of IMGs asserted that their ethnic backgrounds and identification with their respective communities could increase access to care for some segments of the population and therefore should be permitted pathways to qualify as PAs. A variety of legal measures were introduced into state legislatures in at least five states and were firmly opposed and defeated by the PA profession.
View Article and Find Full Text PDFBMC Med Ethics
October 2023
General Practitioner, Shohada Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Background: Since the beginning of the COVID-19 pandemic, different countries sought to manufacture and supply effective vaccines to control the disease and prevent and protect public health in society. The implementation of vaccination has created many ethical dilemmas for humans, which must be recognized and resolved. Therefore, the present study was conducted to analyze the ethical considerations in vaccination against COVID-19 from the perspective of service providers.
View Article and Find Full Text PDFJ Am Assoc Lab Anim Sci
September 2023
Labcorp Early Development Laboratories Limited, Alconbury, United Kingdom.
This study compared euthanasia induced by rising concentrations of CO₂ in aged rats (n = 59) using different gas displacement rates. Rats were preimplanted with cardiovascular telemetry devices and had been previously used for short term safety pharmacology studies. Once fully recovered from previous studies, rats were euthanized using rising concentrations of CO₂.
View Article and Find Full Text PDFSyst Biol
June 2023
Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269, USA.
The Lowest Radial Distance (LoRaD) method is a modification of the recently introduced Partition-Weighted Kernel method for estimating the marginal likelihood of a model, a quantity important for Bayesian model selection. For analyses involving a fixed tree topology, LoRaD improves upon the Steppingstone or Thermodynamic Integration (Path Sampling) approaches now in common use in phylogenetics because it requires sampling only from the posterior distribution, avoiding the need to sample from a series of ad hoc power posterior distributions, and yet is more accurate than other fast methods such as the Generalized Harmonic Mean (GHM) method. We show that the method performs well in comparison to the Generalized Steppingstone method on an empirical fixed-topology example from molecular phylogenetics involving 180 parameters.
View Article and Find Full Text PDFOpen Biol
December 2022
Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
The four dengue viruses (DENVs) have evolved multiple mechanisms to ensure its survival. Among these mechanisms is the ability to regulate its replication rate, which may contribute to avoiding premature immune activation that limit infection dissemination: DENVs associated with dengue epidemics have shown slower replication rate than pre-epidemic strains. Correspondingly, wild-type DENVs replicate more slowly than their clinically attenuated derivatives.
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