Physiologic interactions between macrophages and Leydig cells.

Exp Biol Med (Maywood)

Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

Published: January 2006

AI Article Synopsis

  • This minireview examines the relationship between testicular macrophages and Leydig cells, focusing on how these two cell types interact.
  • Although there is evidence that macrophages can negatively impact Leydig cells, this review emphasizes the positive, stimulatory effects.
  • The discussion aims to highlight the physiological interactions and potential benefits of macrophages in supporting Leydig cell function.

Article Abstract

The purpose of this minireview is to present information concerning the morphologic and functional relationship between testicular macrophages and Leydig cells. Although data concerning the negative influence of macrophage-derived products on testicular Leydig cells exist, this review is focused on the stimulatory influences thought to be involved in the physiologic interactions between these two diverse cell types.

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http://dx.doi.org/10.1177/153537020623100101DOI Listing

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