A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2005.12.006 | DOI Listing |
Publication Analysis
Top Keywords
sglt2 inhibitors
8
indole-glucosides novel
4
novel sodium
4
sodium glucose
4
glucose co-transporter
4
co-transporter sglt2
4
inhibitors series
4
series indole-o-glucosides
4
indole-o-glucosides c-glucosides
4
c-glucosides synthesized
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!