New photoantimicrobial films composed of porphyrinated lipophilic cellulose esters.

Bioorg Med Chem Lett

Université de Limoges, Laboratoire de Chimie des Substances Naturelles, 123 Avenue Albert Thomas, 87060 Limoges cedex, France.

Published: March 2006

Porphyrinated cellulose laurate esters have been prepared in homogeneous DMA/LiCl medium by "one-pot, two-step" reactions starting from cellulose, protoporphyrin IX, and lauric acid and using a TsCl/Pyridine system. The plastic films obtained after casting were shown to display photobactericidal activity against Gram positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria. This new photobactericidal polymer has potential for industrial, medical, or household applications.

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http://dx.doi.org/10.1016/j.bmcl.2005.12.008DOI Listing

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