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Transposition of the great arteries with an intact ventricular septum in older children.

Cardiol Young

December 2024

Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha, China.

Complete transposition of the great arteries is a common life-threatening complex cyanotic congenital heart disease in infants, resulting in the operation usually performed about one week after birth. However, little is known about the surgical strategy and experience of transposition of the great arteries with an intact ventricular septum in older patients. Herein, we present an abandoned 7-year-old boy with severe cyanosis with clubbed fingers and toes and then diagnosed with transposition of the great arteries with an intact ventricular septum, atrial septal defect, patent ductus arteriosus, and pulmonary hypertension.

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Introduction: The safety of continuing anticoagulation therapy during endoscopic variceal ligation (EVL) remains controversial. We performed a systematic review and meta-analysis to evaluate the safety of anticoagulation therapy in EVL.

Methods: We systematically searched four electronic databases from their inception until 1 June 2024, for studies that evaluated anticoagulation use and risk of rebleeding among patients undergoing EVL.

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Article Synopsis
  • This study aimed to analyze the hemodynamics of a new animal model of Fontan physiology, which is important for understanding poor long-term outcomes in Fontan patients.
  • Researchers created a single-stage Fontan model in juvenile sheep and conducted detailed hemodynamic assessments.
  • Results showed that only a fraction of the sheep survived, with survival rates improving over time due to a learning curve; the study identified key hemodynamic characteristics but noted anatomical differences that affected the model's accuracy, suggesting surgical modifications could enhance future studies.
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Article Synopsis
  • The surgical management of critical aortic stenosis and associated heart conditions in neonates poses a complex challenge regarding the recovery of left ventricular function post-surgery.
  • In a described case, a premature neonate with critical aortic stenosis and severe mitral regurgitation underwent a series of surgeries, including pulmonary artery banding and aortic valvuloplasty, to stabilize heart function.
  • Ultimately, the staged biventricular repair led to a successful outcome, with the patient showing stable health six years after the operations.
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Background/aims: Endoscopic band ligation (EBL) standard therapy is traditionally performed with banding from the distal esophagus upwards. However, esophageal varices (EV) with stigma of recent bleeding are not consistently banded at the first attempt. We aimed to compare conventional banding in acute variceal bleeding (AVB) vs targeted banding of EV in patients with stigma of recent bleeding (white nipple sign).

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