Objective: The purpose of this study was to evaluate the feasibility of sonographically guided percutaneous muscle biopsy in the investigation of neuromuscular disorders.
Methods: Sonographically guided percutaneous needle biopsy of skeletal muscle was performed with a 14-gauge core biopsy system in 40 patients over a 24-month period. Patients were referred from the Department of Neurology under investigation for neuromuscular disorders. Sonography was used to find suitable tissue and to avoid major vascular structures. A local anesthetic was applied below skin only. A 3- to 4-mm incision was made. Three 14-gauge samples were obtained from each patient. All samples were placed on saline-dampened gauze and sent for neuropathologic analysis. As a control, we retrospectively assessed results of the 40 most recent muscle samples acquired via open surgical biopsy.
Results: With the use of sonography, 32 (80%) of 40 patients had a histologic diagnosis made via percutaneous needle biopsy. This included 26 (93%) of 28 patients with acute muscular disease and 6 (50%) of 12 patients with chronic disease. In the surgical group (all acute disease), 38 (95%) of 40 patients had diagnostic tissue attained.
Conclusions: Sonographically guided percutaneous 14-gauge core skeletal muscle biopsy is a useful procedure, facilitating diagnosis in acute muscular disease. It provides results comparable with those of open surgical biopsy in acute muscular disease. It may also be used in chronic muscular disease but repeated or open biopsy may be needed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.7863/jum.2006.25.1.1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrasound imaging of the femoral and saphenous nerves.
Australas J Ultrasound Med
November 2024
Imaging Associates Group Box Hill Victoria Australia.
Introduction: Iatrogenic and traumatic injuries to the femoral and saphenous nerves, and their branches are uncommon but can be a cause of clinically pertinent lower limb dysfunction and neuralgia. Despite this, direct sonographic imaging of these nerves is not commonly requested or performed.
Methods: A review of the literature regarding the detailed relative anatomy, sonographic technique to image these nerves and their branches and their normal and abnormal appearances was conducted.
PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System.
J Imaging
December 2024
Obstetrics and Gynaecology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari, 70124 Bari, Italy.
This study aimed to evaluate our center's experience in diagnosing and managing placenta accreta spectrum (PAS) in a high-risk population, focusing on prenatal ultrasound features associated with PAS severity and maternal outcomes. We conducted a retrospective analysis of 102 high-risk patients with confirmed placenta previa who delivered at our center between 2018 and 2023. Patients underwent transabdominal and transvaginal ultrasound scans, assessing typical sonographic features.
View Article and Find Full Text PDFCorrelation between sonographic classification and the efficacy of microwave ablation for adenomyosis.
Quant Imaging Med Surg
December 2024
Department of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Background: Adenomyosis is a common benign gynecological disease. Patients often experience abnormal uterine bleeding, dysmenorrhea, and infertility. Percutaneous microwave ablation (PMWA) is a minimally invasive method used for treating adenomyosis while preserving the uterus.
View Article and Find Full Text PDFReal-World Safety and Efficiency of Treating Symptomatic Varicose Veins with Endovenous Closure of Great, Small, and Anterior Accessory Veins Using Cyanoacrylate Glue (VenaSeal™): A Single-surgeon Multicenter Retrospective Study.
Ann Vasc Surg
December 2024
Vascular Surgery, Department of Surgery, Frankston Hospital, Peninsula Health, Melbourne, Victoria, Australia.
Background: Treatment of symptomatic varicose veins has changed dramatically in the last few years with guidelines now recommending endovenous surgery as first-line intervention. Previously, this was achieved by laser or radiofrequency ablation of the target vein, requiring infiltration of tumescent anesthesia to reduce the risks of thermal damage to surrounding tissue. Endovenous cyanoacrylate injection (VenaSeal™) is a nonthermal, nontumescent endovenous closure technique, increasing patient comfort and is readily performed under local anesthesia only and thus is a feasible technique for in-room treatment.
View Article and Find Full Text PDFReal time continuous monitoring of injection pressure at the needle tip is better than ultrasound in early detecting intraneural injection.
Reg Anesth Pain Med
December 2024
Anesthesia, Ospedale Regionale di Bellinzona e Valli Bellinzona, Bellinzona, Switzerland.
Article Synopsis
- Inadvertent intraneural injections during peripheral nerve blocks are common, and this study compares two detection methods: injection pressure monitoring and ultrasound imaging.
- The research involved anesthesiologists conducting intraneural injections on fresh cadaver arms, measuring both pressure and sonographic images to evaluate outcomes.
- Results showed that pressure monitoring detected intraneural injection much earlier than ultrasound (after just 0.2 mL vs. 1.2 mL for swelling), confirming that pressure monitoring is a more sensitive technique.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!