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Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates. | LitMetric
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Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates.

Patrick Vallance Hannah D Bush B James Mok Ramon Hurtado-Guerrero Herpreet Gill Sharon Rossiter Jonathan D Wilden Stephen Caddick

Chem Commun (Camb)

Department of Medicine, Rayne Building, 5 University Street London, WC1E 6JJ, UK.

Published: November 2005

A range of pentafluorophenyl (PFP) sulfonate esters derived from the reaction of PFP vinyl sulfonate and various nitrones are shown to have significant inhibitory activity against the bacterial enzymes DDAH and ADI.

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 Source
http://dx.doi.org/10.1039/b510709aDOI Listing

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