The unexpected appearance of a new polymorph of maleic acid is reported and a computational study addresses the predictability of this new polymorph and future potential polymorphism.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/b513442k | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characterization of Quality Marker for Mume Fructus Pulp by Ultra-Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Untargeted Metabolomics Combined With Biological Activities.
Phytochem Anal
January 2025
College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Introduction: As a widely used Chinese herbal medicine, Mume Fructus pulp (MFP) has rich nutritional value and biological activity, but its quality control research is relatively scarce.
Objectives: The objective of the study was to evaluate the quality difference between MFPs from different origins and its adulterant apricot pulp (APP), and to identify potential quality markers.
Methods: The chemical compositions were identified by untargeted metabolomics analysis based on ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry combined with feature-based molecular networking.
Comparison of lipid dynamics and permeability in styrene-maleic acid and diisobutylene-maleic acid copolymer lipid nanodiscs by electron paramagnetic resonance spectroscopy.
J Biol Inorg Chem
January 2025
Department of Chemistry and Biochemistry, Miami University, Oxford, OH, USA.
Lipid nanoparticles formed with copolymers are a new and increasingly powerful tool for studying membrane proteins, but the extent to which these systems affect the physical properties of the membrane is not completely understood. This is critical to understanding the caveats of these new systems and screening for structural and functional artifacts that might be caused in the membrane proteins they are used to study. To better understand these potential effects, the fluid properties of dipalmitoylphosphatidylcholine lipid bilayers were examined by electron paramagnetic resonance (EPR) spectroscopy with spin-labeled reporter lipids in either liposomes or incorporated into nanoparticles with the copolymers diisobutylene-maleic acid or styrene maleic acid.
View Article and Find Full Text PDFUltra-stretchable, self-recoverable, notch-insensitive, self-healable and adhesive hydrogel enabled by synergetic hydrogen and dipole-dipole crosslinking.
Mater Horiz
January 2025
College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, China.
Hydrogels are promising materials for wearable electronics, artificial skins and biomedical engineering, but their limited stretchability, self-recovery and crack resistance restrict their performance in demanding applications. Despite efforts to enhance these properties using micelle cross-links, nanofillers and dynamic interactions, it remains a challenge to fabricate hydrogels that combine high stretchability, self-healing and strong adhesion. Herein, we report a novel hydrogel synthesized the copolymerization of acrylamide (AM), maleic acid (MA) and acrylonitrile (AN), designed to address these limitations.
View Article and Find Full Text PDFThermally Solvent-Free Cross-Linked pH/Thermosensitive Hydrogels as Smart Drug Delivery Systems.
Gels
December 2024
"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.
An imbalance in the body's pH or temperature may modify the immune response and result in ailments such as autoimmune disorders, infectious diseases, cancer, or diabetes. Dual pH- and thermo-responsive carriers are being evaluated as advanced drug delivery microdevices designed to release pharmaceuticals in response to external or internal stimuli. A novel drug delivery system formulated as hydrogel was developed by combining a pH-sensitive polymer (the "biosensor") with a thermosensitive polymer (the delivery component).
View Article and Find Full Text PDFTunable Terpolymer Series for the Systematic Investigation of Membrane Proteins.
Biomacromolecules
January 2025
Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.
Membrane proteins (MPs) are critical to cellular processes and serve as essential therapeutic targets. However, their isolation and characterization are often impeded by traditional detergent-based methods, which can compromise their native states, and retention of their native lipid environment. Amphiphilic polymers have emerged as effective alternatives, enabling the formation of nanoscale discs that preserve MPs' structural and functional integrity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!