We report a case of a massive mediastinal teratoma in an 18-year-old woman who presented with a short history of exertional dyspnoea. The tumor arose from the left lobe of the thymus and extended into the left pleural cavity, completely compressing the left lung and extensively shifting the mediastinum to the right. Measuring 23 cm x 17 cm x 9 cm and weighing 2005 g it is one of the largest anterior mediastinal teratomas reported. It was successfully treated by surgical resection, with a final pathological diagnosis of a grades 1-2 immature teratoma.
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http://dx.doi.org/10.1016/j.hlc.2004.11.001 | DOI Listing |
Gen Thorac Cardiovasc Surg Cases
December 2024
Department of Surgery II, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata, Japan.
Background: Mature teratomas are benign cystic tumors that are most commonly asymptomatic. However, in some cases, mediastinal teratomas rupture the lungs and mediastinum with potentially fatal outcomes. Herein, we report a case of a large mediastinal mature teratoma that expanded to the entire left hemithorax in a child with common cold-like symptoms.
View Article and Find Full Text PDFKyobu Geka
November 2024
Department of General Thoracic, Breast and Endocrinological Surgery, Kagawa University, Kagawa, Japan.
A 36-year-old woman referred to our hospital for treatment of a mediastinal tumor. Contrast computed tomography (CT) scan was revealed a 31×21×25 mm mass in the anterior mediastinum, with low contrast, clear border, and a tendency to increase. On magnetic resonance imaging( MRI) examination, the anterior mediastinal tumor showed homogeneous high signal intensity on T1-weighted images and a combination of high and low signal intensities on T2-weighted images.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Department of Ultrasound, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Cureus
November 2024
Prenatal Diagnostic Department, Unidade Local de Saúde Almada-Seixal, Almada, PRT.
Fetal mediastinal teratomas are rare tumors that can lead to serious complications such as fetal hydrops and intrauterine fetal death. Early prenatal diagnosis is critical in patient counseling, management, and preparation for postnatal interventions. In this report, we present the case of a 27-year-old woman in the second trimester of a dichorionic diamniotic twin pregnancy, in which the presenting fetus was diagnosed with a mediastinal teratoma and subsequently developed fetal hydrops, leading to intrauterine death.
View Article and Find Full Text PDFFront Oncol
November 2024
Medical Oncology Unit, Department of Systems Medicine, University Tor Vergata, Rome, Italy.
The treatment of patients affected by a teratoma with somatic-type malignancy (STM) is challenging, since they are characterized by a poor prognosis, due to chemoresistance to standard cisplatin-based regimens. Only five more case reports were described for melanomatous STM and for which there are no data available for efficacy evidences of immune checkpoint inhibitors in this setting. Here we report the case of a patient with an initial diagnosis of mediastinal pure seminoma at the first biopsy.
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