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| http://dx.doi.org/10.1128/br.12.1.79-103.1948 | DOI Listing |
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Diagnostic performance of automated red cell parameters in predicting bone marrow iron stores.
Clin Chem Lab Med
February 2024
United Laboratories, Tartu University Hospital, Tartu, Estonia.
Objectives: The aim of the study was to determine the diagnostic performance of novel automated red cell parameters for estimating bone marrow iron stores.
Methods: The study was a retrospective single-centre study based on data from an automated haematology analyser and results of bone marrow iron staining. Red cell parameters were measured on a Sysmex XN-series haematology analyser.
Synergistic Antifungal Interactions between Antibiotic Amphotericin B and Selected ,,-thiadiazole Derivatives, Determined by Microbiological, Cytochemical, and Molecular Spectroscopic Studies.
Int J Mol Sci
February 2023
Department of Cell Biology, Maria Curie-Sklodowska University, Akademicka 19, 20-033 Lublin, Poland.
In recent years, drug-resistant and multidrug-resistant fungal strains have been more frequently isolated in clinical practice. This phenomenon is responsible for difficulties in the treatment of infections. Therefore, the development of new antifungal drugs is an extremely important challenge.
View Article and Find Full Text PDFMorphological and biochemical analysis of cells cultured on fibrous poly(ε-caprolactone) scaffolds with different degrees of fiber alignment produced by solution blow spinning.
Artif Organs
August 2023
Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC, São Bernardo do Campo, Brazil.
Background: Bioresorbable materials are compounds that decompose in physiological mediums both in vitro and in vivo and are used as an alternative to temporary implants in injured tissues. The aim of this study was to analyze the morphology and cytochemistry of cells grown on fibrous poly(ε-caprolactone) (PCL) scaffolds and to measure cell metabolism parameters by biochemical analysis of the conditioned culture medium from cells grown on the scaffolds.
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The Early Peritoneal Cavity Immune Response to Infection and to Inactivated Bacterium in Olive Flounder ().
Microorganisms
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Laboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, 5 Yushan Road, Qingdao 266003, China.
The peritoneal cavity plays an important role in the immune response, and intraperitoneal administration is an ideal vaccination route in fish. However, immune responses in the peritoneal cavity of teleost fish are still not completely characterized. This study characterized the morphology of peritoneal cavity cells (PerC cells) and their composition in flounder ().
View Article and Find Full Text PDFCytochemical Characterization of Cerebrospinal Fluid Macrophage Inclusions in Pediatric Patients Receiving Intrathecal Nusinersen (SPINRAZA®) for Spinal Muscular Atrophy.
Acta Cytol
March 2022
Department of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona, USA.
Introduction: Spinal muscular atrophy (SMA) is a debilitating neuromuscular disorder caused by biallelic deletion of the SMN1 gene. Nusinersen, an antisense oligonucleotide delivered intrathecally, binds to the pre-mRNA of SMN1's pseudogene, SMN2, to prevent exon skipping and produce functional SMN protein to compensate for the deficiency caused by SMN1 deletion.
Case Presentation: We reviewed 15 cerebrospinal fluid (CSF) cytology specimens from 8 patients receiving nusinersen for SMA.
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