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Introduction: Recently, studies have suggested a role of motor symptom asymmetry on impaired emotional recognition abilities in Parkinson's disease with a greater vulnerability in patients with a predominance of left-sided symptoms. However, none of them explored the interaction between motor symptom asymmetry and dopamine replacement therapy in different stages of the disease.
Methodology: We explored the recognition of vocal emotion (i.
Constant Desbordes Painting of Jean-Louis Alibert Administering the Smallpox Vaccine ("La Vaccine"): An Historic Vaccination or Artistic Imagination?
Clin Dermatol
December 2024
Jefferson Center for International Dermatology and Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
In 1822, France's Ministry of the Interior, concerned about dropping vaccination rates among the population, commissioned the French artist Constant Joseph Desbordes (1761-1828) to create an artwork that would educate the public about the benefits of the smallpox vaccine. The Painting that resulted is entitled: "La Vaccine" ("The Cowpox Inoculation") and a copy of it is entitled "La Vaccine au Chateau de Liancourt" ("Performing the Vaccination against Smallpox in the Chateau of Liancourt"). The highlight of the painting is its central figure, one of France's most distinguished physicians, Jean-Louis Alibert (1768-1837) performing, in dramatic fashion, the arm to arm method of smallpox vaccination that was common at that time.
View Article and Find Full Text PDFChildren with Stroke: An Investigation of Their Home Environment.
Stud Health Technol Inform
November 2024
Chair of Social and Health Care Buildings and Design, Faculty of Architecture, Technische Universität Dresden, Germany.
Existing research on stroke in adults highlights the role of the built environment during recovery. However, this role has been greatly overlooked in the everyday lives of children with stroke. A stroke in childhood brings substantial changes for affected individuals and their families.
View Article and Find Full Text PDFA Case of Left-Sided Infective Endocarditis Secondary to Intravenous Drug Use Resulting in Septic Renal Emboli.
Cureus
October 2024
Internal Medicine, Richmond University Medical Center, New York, USA.
Methicillin-sensitive (MSSA) is a gram-positive, coagulase-positive coccus implicated in the pathogenesis of infective endocarditis (IE) due to intravenous drug use (IDU). The tricuspid valve is the most commonly affected valve; however, there is an increased incidence of mitral valve involvement. In this case report, we present a 41-year-old female with no known past medical history but a social history significant for IDU who presented with MSSA bacteremia, sepsis, and IE with vegetations on the mitral valve.
View Article and Find Full Text PDFLet's focus on the insula in addiction: A refined anatomical exploration of insula in severe alcohol and cocaine use disorders.
Eur Psychiatry
November 2024
Normandie Université, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", NeuroPresage Team, Cyceron, Caen, France.
Article Synopsis
- The study investigates the changes in gray matter (GM) volume in the insula, a brain region linked to addiction, comparing severe alcohol use disorder (sAUD) and severe cocaine use disorder (sCUD).
- Researchers analyzed 12 subregions of the insula using a sample of 50 sAUD patients, 61 sCUD patients, and 36 healthy controls, finding overall lower insula volume in both disorders, particularly in the anterior long gyrus (ALG).
- The results highlight both shared and distinct patterns of insula volume deficits between sAUD and sCUD, suggesting that while the insula is important in substance use disorders, each disorder may have unique characteristics that could inform treatment approaches.
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