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Intestinal polyps and chronic schistosomiasis.
Rev Esp Enferm Dig
March 2025
General Practitioner, University of Americas, Brazil.
Intestinal polyps have been described in association with chronic schistosomiasis, and must be differentiated from malignant tumors and appropriately managed. This uncommon condition may be very rarely detected in people from non-endemic areas of this zoonosis, who were occasionally infected during some travel period. The lesions are more frequently described in men, and predominating in the colon.
View Article and Find Full Text PDFNetwork pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer.
Hereditas
March 2025
Department of Gastroenterology, Renmin Hospital of Wuhan University, Zhongxiang, Hubei, 431900, China.
Background And Objective: Changweiqing (CWQ) is a Chinese herbal formula for the treatment of the gastrointestinal tract diseases, but its role in the treatment of colorectal cancer (CRC) has not been clarified. This study aimed to explore the molecular mechanism of CWQ in CRC treatment through bioinformatics analysis and network pharmacology.
Methods: Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform and SwissTargetPrediction database were used to collect the bioactive components of CWQ.
Pheochromocytoma in a patient with heterotaxy syndrome: a case report.
BMC Endocr Disord
March 2025
Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran.
Background: Heterotaxy syndrome is a rare congenital condition characterized by abnormal arrangement of thoracoabdominal organs, often associated with complex cardiac and splenic anomalies. Pheochromocytoma is a rare neuroendocrine tumor that overproduces catecholamines, leading to various complications. The co-occurrence of heterotaxy syndrome and pheochromocytoma has not been previously reported.
View Article and Find Full Text PDFRisk Factors, Clinical Course, and Management of Delayed Perforation After Colorectal Endoscopic Submucosal Dissection: A Large-Scale Multicenter Study.
Dig Dis Sci
March 2025
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-Cho, Kawaramachi-Hirokoji, Kamigyo-Ku, Kyoto, 602-8566, Japan.
Introduction: Delayed perforation (DP) remains a significant complication of colorectal endoscopic submucosal dissection (ESD). This study analyzed the risk factors, clinical course, and management for DP following colorectal ESD.
Methods: We retrospectively reviewed 4,632 consecutive colorectal ESD cases from 13 institutions between January 2006 and May 2024.
A histopathological snapshot of bladder cancer: a Johannesburg experience of 1480 histopathology reports.
World J Urol
March 2025
Department of Anatomical Pathology, University of the Witwatersrand, /National Health Laboratory Services, Johannesburg, South Africa.
Purpose: To evaluate the histopathological characteristics of bladder cancer in patients presenting to Johannesburg hospitals over a 13-year period (2010-2023).
Methods: Following ethical clearance, a retrospective observational, descriptive review of histopathological reports over 13 years was conducted in Johannesburg. Inclusion criteria was bladder biopsies, TURBT specimens, and radical cystectomy (RC) specimens positive for bladder cancer.
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