Five-month-old lambs were simultaneously infected with different doses of two 16S rRNA genetic variants of Anaplasma phagocytophilum and thereafter followed for clinical observation and blood sampling. The result of the study indicates a unidirectional suppression of genotypes in infected lambs, at least during a certain period of an A. phagocytophilum infection.
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http://dx.doi.org/10.1128/CDLI.12.12.1448-1450.2005 | DOI Listing |
Cogn Neurodyn
December 2024
School of Physics, Zhejiang University of Technology, Hangzhou, 310023 China.
The output of the basal ganglia to the corticothalamic system plays an important role in regulating absence seizures. Inspired by experiments, we systematically study the crucial roles of two newly identified direct inhibitory striatal-cortical projections that project from the striatal D1 nucleus (SD1) and striatal D2 nucleus (SD2) to the cerebral cortex, in controlling absence seizures. Through computational simulation, we observe that typical 2-4 Hz spike and wave discharges (SWDs) can be induced through the pathological mechanism of cortical circuits, and both enhancing the inhibitory coupling weight on the striatal-cortical projections and improving the discharge activation level of striatal populations can effectively control typical SWDs.
View Article and Find Full Text PDFNanophotonics
January 2024
Departament de Física, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.
Adv Mater
December 2024
School of Physics, and State Key Laboratory of Silicon Materials and Advanced Semiconductor Materials, Zhejiang University, Hangzhou, 310027, China.
Cells
November 2024
Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
In cells, the main enzymes involved in pentose interconversion are ribose-5-phosphate isomerases RpiA and RpiB and ribulose-5-phosphate epimerase Rpe. The inactivation of limits ribose-5-phosphate (R5P) synthesis via the oxidative branch of the pentose phosphate pathway (PPP) and unexpectedly results in antibiotic supersensitivity. This type of metabolism is accompanied by significant changes in the level of reducing equivalents of NADPH and glutathione, as well as a sharp drop in the ATP pool.
View Article and Find Full Text PDFBidirectional feedback by fiber Bragg grating arrays (FBGAs) reduced the loss of the cavity and increased stimulated Brillouin scattering (SBS) gain by bi-directional Stokes wave through FBGA associated Rayleigh feedback of the pump wave. As a result, the Q value of the Brillouin random fiber laser (BRFL) increased significantly, which leads to narrow linewidth. This is different from the ring configuration with unidirectional SBS gain versus dual SBS gain of the same fiber length.
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