AI Article Synopsis
- A case study details a patient who developed Nocardia asteroides keratitis three weeks after undergoing LASIK in a nontraumatized eye, leading to vision loss and inflammation.
- The initial treatment with topical antibiotics failed, necessitating a penetrating keratoplasty (PKP) surgery to address the severe infection.
- After surgery, the patient experienced a recurrence of the infection at the graft-host interface, which was successfully treated with a combination of moxifloxacin and imipenem.
Article Abstract
A case of Nocardia asteroides keratitis occurring 3 weeks after laser in situ keratomileusis (LASIK) in a nontraumatized eye is reported. The patient presented with decreased vision, inflammation, and stromal melting of the LASIK flap, discrete infiltrates, and an anterior chamber cellular reaction. Cultures for acid-fast bacteria grew Nocardia asteroides after 5 days. Infection progressed despite treatment with topical antibiotics and eventually required penetrating keratoplasty (PKP). Postoperatively, the patient was placed on moxifloxacin, a fourth-generation flouroquinolone. The patient experienced a recurrence of Nocardia keratitis at the graft-host interface 2 months after the PKP. This eventually resolved with a combination of topical moxifloxacin and imipenem therapy.
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| http://dx.doi.org/10.1016/j.jcrs.2005.02.049 | DOI Listing |
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