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Associations Between Lead and Cadmium Exposure and Subclinical Cardiovascular Disease in U.S. Adults.
Cardiovasc Toxicol
January 2025
Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
The impact of lead and cadmium exposure on subclinical cardiovascular disease (CVD), indicated by elevated high-sensitivity cardiac troponin (hs-cTnT) and N-terminal pro b-type natriuretic peptide (NT-proBNP) remains uncertain. We analyzed data from participants aged 20 and older, without overt CVD, in the National Health and Nutrition Examination Survey (NHANES; 1999-2004). Elevated lead and cadmium levels were defined as 3.
View Article and Find Full Text PDFAdvanced Machine Learning to Predict Coronary Artery Disease Severity in Patients with Premature Myocardial Infarction.
Rev Cardiovasc Med
January 2025
Thoracic Clinical College, Tianjin Medical University, 300070 Tianjin, China.
Background: Studies using machine learning to identify the target characteristics and develop predictive models for coronary artery disease severity in patients with premature myocardial infarction (PMI) are limited.
Methods: In this observational study, 1111 PMI patients (≤55 years) at Tianjin Chest Hospital from 2017 to 2022 were selected and divided according to their SYNTAX scores into a low-risk group (≤22) and medium-high-risk group (>22). These groups were further randomly assigned to a training or test set in a ratio of 7:3.
Association of ST2, Galectin-3, and NT- Probnp in Elderly Hypertensive Patients and Heart Failure with a Preserved Ejection Fraction.
Curr Vasc Pharmacol
January 2025
Department of oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Purpose: The objective of this study was to explore the relationship among serum levels of the growth-stimulating expressed gene 2 protein (ST2), Galectin-3(GAL-3), N-terminal pro-B-type natriuretic peptide (NT-proBNP) in elderly hypertensive patients and heart failure with preserved ejection fraction (HFpEF).
Materials And Methods: Eighty-five elderly hypertensive patients with HFpEF were registered as the HFpEF group, and 46 hypertensive patients without HF were registered as the Non-HF group. The levels of serum sST2 (soluble ST2), Galectin-3, and NT-proBNP were measured, and related indexes of heart function were performed with echocardiography in two groups, respectively.
[Predictive model for ejection fraction improvement at one year in patients with acute ST-segment elevation myocardial infarction complicated with heart failure with reduced ejection fraction].
Zhonghua Yi Xue Za Zhi
January 2025
Ningbo Hangzhou Bay Hospital(Ningbo Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai),Ningbo315336, China.
To develop a predictive model for improvement of ejection fraction 1 year after heart failure with reduced ejection fraction (HFrEF) following acute ST-segment elevation myocardial infarction (STEMI). This nested case-control study included STEMI patients diagnosed with HFrEF from a prospective multicenter multimodality imaging cohort between August 2014 and March 2021. Based on the improvement of left ventricular ejection fraction (LVEF) at baseline and 1-year follow-up, the patients were classified into the heart failure with improved ejection fraction (HFimpEF) group and the persistent HFrEF group.
View Article and Find Full Text PDFA new simple chronic heart failure prognostic index based on five general parameters.
Int J Cardiol
January 2025
Internal Medicine Department, Centro Hospitalar e Universitário São João, Portugal; Department of Medicine, Faculty of Medicine of University of Porto, Portugal. Electronic address:
Background: Prognostic prediction in heart failure (HF) is challenging and no single marker has proven effective. We propose an index based on B-type natriuretic peptide (BNP) and four widely available parameters.
Methods: We retrospectively analyzed adult outpatients with chronic HF with systolic dysfunction followed from January 2012 to December 2020.
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