Squamous cell carcinoma of the lower lip: exact location match in siblings.

Background: In recent years, genetic contribution to the development of skin cancers is under the magnifying glass of several authors and is now regarded as the main initial etiology in carcinogenesis.

Objective: Two siblings who had squamous cell carcinoma of the lower lip showing an exact location match are presented.

Patients: They did not share common environmental factors, and there was no history of tobacco and/or alcohol abuse.

Conclusions: It would be scientifically deceptive to draw generous conclusions for the cases here, other than being a very interesting and unusual coincidence, because further evaluation could not be done to scientifically prove a possible genetic contribution.