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A hypertensive adolescent with aripiprazole-induced hyperaldosteronism.
Pediatr Nephrol
December 2024
Department of Pediatrics, Division of Nephrology, Izmir City Hospital, Izmir, Turkey.
Article Synopsis
- A 16-year-old male developed hypertension after starting aripiprazole, an antipsychotic medication.
- Medical evaluations revealed elevated aldosterone/plasma renin activity (PRA) initially, but levels normalized after the patient stopped taking the drug.
- This case highlights the potential link between aripiprazole and hypertension, suggesting that the drug may contribute to hyperaldosteronism in some patients.
Prevalence of and factors associated with overweight and obesity in patients with severe mental disorders in Shenzhen: results from the urban Chinese population.
Public Health Nutr
November 2024
Department of Public Health, Shenzhen Mental Health Center, Shenzhen Kangning Hospital, Shenzhen, Guangdong, China.
Article Synopsis
- The study investigates the prevalence of overweight and obesity among patients with severe mental disorders (SMD) in Shenzhen, China, with a focus on socio-demographic and disease-related factors.
- Among the 14,868 patients analyzed, the prevalence rates were found to be 32.6% for overweight and 16.1% for obesity.
- Key factors associated with higher chances of being overweight or obese included marital status, length of management, specific medications, and various health indicators such as hypertension and high blood sugar levels, indicating a need for better management strategies in this population.
Introduction: This paper aims to examine the frequency and significance of diagnostic comorbidity of psychiatric disorders and somatic diseases in a sample of patients with depression as well as present current psychopharmacological treatment of the patients in the sample.
Methods: The subjects in this study sample were 489 patients from the four Western Balkan countries with current primary diagnosis of major depression according to ICD 10. Comorbid psychiatric disorders and non-psychiatric illnesses were noted according to ICD 10 criteria during the diagnostic interview and analysed later.
Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like Syndromes in Rats and Stable Gastric Pentadecapeptide BPC 157 as Therapy.
Pharmaceuticals (Basel)
May 2023
Department of Pharmacology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Even before behavioral disturbances, neuroleptics, amphetamine, and domperidone application rapidly emerged severe occlusion/occlusion-like syndrome, shared innate vascular and multiorgan failure in rats, comparable to occlusion/occlusion-like syndrome described with vessel(s) occlusion or similar noxious procedures application. As therapy, i.e.
View Article and Find Full Text PDFAntipsychotic-Induced Metabolic Syndrome: A Review.
Metab Syndr Relat Disord
August 2023
Faculté de Pharmacie, Université Laval, Québec, Canada.
Schizophrenia, a serious psychiatric disorder, is among the top 10 global causes of disability and affects nearly 1% of the world population. Antipsychotics constitute the best treatment for patients with schizophrenia, however, this treatment class carries a high risk of metabolic syndrome, including lipid abnormalities. Indeed, the risk of metabolic syndrome would be increased in the population with schizophrenia compared to the general population.
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