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Increased Incidence of Surgical Intervention for Otitis Media With Effusion Among Patients With Type 2 Inflammatory Diseases.
J Allergy Clin Immunol Pract
January 2025
Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa.
Background: Otitis media with effusion (OME) is associated with comorbidities such as allergic rhinitis, gastroesophageal reflux disease, asthma, and more. Many of these comorbidities can be caused by type 2 inflammation (T2I). This study aims to determine the risk of undergoing OME surgery in patients with and without T2I disease.
View Article and Find Full Text PDFCOCHLEA: Longitudinal Cognitive Performance of Older Adults with Hearing Loss and Cochlear Implants at 4.5-Year Follow-Up.
Brain Sci
December 2024
Department of Audiology and Speech Pathology, The University of Melbourne, 550 Swanston Street, Carlton, VIC 3010, Australia.
Objectives: Hearing loss is highly prevalent in older adults and is independently associated with accelerated cognitive decline. Cochlear implants are usually the only effective treatment for people with severe-profound hearing loss, who have the highest risk of cognitive decline and dementia, however, very few receive them. Current evidence of the effects of cochlear implant use on cognitive decline/dementia outcomes is limited and unclear.
View Article and Find Full Text PDF[The path to advancement in endoscopic ear surgery].
Zhonghua Yi Xue Za Zhi
December 2024
Department of Otolaryngology-Head and Neck Surgery, Eye and ENT Hospital of Fudan University, Shanghai Auditory Medical Center, National Health Commission Key Laboratory of Auditory Medicine, Shanghai200031, China.
Endoscopic ear surgery is currently widely applied in middle ear and lateral skull base procedures, driving the development of ear surgery towards minimally invasive approaches and function preservation. Endoscopic techniques offer many advantages. However, the learning curve is relatively steep, requiring surgeons to overcome challenges such as single-handed operation and a lack of spatial awareness.
View Article and Find Full Text PDFLong-range enhancers maintain competency for hair cell regeneration in the inner ear.
Proc Natl Acad Sci U S A
December 2024
Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles CA 90033.
During tissue regeneration, lineage-related cells can switch their fate to replace missing cells. This cell plasticity is particularly prominent in more regenerative vertebrates such as zebrafish, yet the molecular basis by which cells transdifferentiate into another cell type upon injury remains unclear. Here, we investigate the epigenetic basis of regenerative transdifferentiation in the inner ear, where supporting cells (SCs) generate mechanosensory hair cells (HCs) upon damage.
View Article and Find Full Text PDFSuperiorly Based Preauricular Flap for Total Ear Lobe Reconstruction Following a Large Keloid Excision.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Engineering Sciences & Allied Sciences, Bharati Vidyapeeths College of Engineering for Women, Pune, India.
A large keloid on the right earlobe that extended to the infraauricular region was the reason for the 42-year-old woman's referral for treatment. The entire thickness of the earlobe was implicated in the surgical defect that resulted from the severe keloid excision. We employed a straightforward technique to provide a pleasing appearance while repairing the entire lobe in a single stage without the need for grafts.
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