[Comparative histologic study of implants (magnets) in orbits of female rabbits].

Arq Bras Oftalmol

Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP.

Published: June 2006

AI Article Synopsis

  • The study aimed to evaluate the microscopic signs of inflammation caused by the fixation of a gold-covered magnet implant in the eye area of rabbits.
  • A total of 54 adult female rabbits were divided into three groups, with evaluations at 1, 3, and 6 weeks post-surgery, using various methods for implant fixation.
  • Results showed signs of inflammation were present up to six weeks postoperatively, with a predominance of chronic inflammation and scar tissue formation, but no significant statistical differences between the fixation methods.

Article Abstract

Purpose: To evaluate microscopically the signs of inflammatory reaction due to the fixation of an orbitary implant (magnet, covered by gold).

Methods: An experimental study was performed in 54 adult female rabbits, divided into 3 groups of eighteen with 3 subgroups of 6; an evaluation at 1, 3 and 6 postoperative weeks was performed. An implant (magnet, covered by gold) was fixed in the inferior orbital rim using biologic glue, screw or unabsorbable suture (Mersilene 5.0). The opposite orbits (without implants) represented the control group.

Results: Microscopic signs of inflammatory reaction due to orbitary fixation of the implant were observed with the use of the three methods (biologic glue, screw or unabsorbable suture) (Mersilene 5.0), until six weeks of the postoperatory period.

Conclusions: Histopathological signs of inflammatory reaction to the implant and to its orbital fixation were observed up to the sixth week, with cyanoacrylate, screw, or unabsorbable suture (Mersilene 5.0), with prevalence of the chronic inflammatory process and cicatricial fibrosis, without statistically significant difference in most of the cases.

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Source
http://dx.doi.org/10.1590/s0004-27492005000500018DOI Listing

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