Purpose: Heidelberg retina tomograph II (HRTII) examination was performed with cornea module in one patient with Acanthamoeba keratitis (AK) to provide images detailing characteristic findings of the disease.
Methods: A 34-year-old woman presented with clinical signs and symptoms of AK. HRTII with cornea module was performed and the patient underwent laboratory investigations.
Results: HRTII examination with cornea module revealed numerous 20-26-micro m diameter high-contrast round particles within the corneal epithelium and anterior stroma, resembling Acanthamoeba cysts. Stellate cells as well as ovoid irregular objects, possibly inflammatory cells, trophozoites, altered cysts, or activated keratocytes, were also present in the area of stromal infiltrates. Laboratory investigations confirmed the diagnosis of AK.
Conclusions: HRTII cornea module can be helpful in the diagnosis of AK by identifying acanthamoeba cyst-like structures in the cornea. This technique also has potential uses in monitoring the efficiency of anti-infective treatment.
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http://dx.doi.org/10.1080/09273940590951098 | DOI Listing |
Vet Ophthalmol
September 2024
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Objective: To describe the in vivo confocal microscopy (IVCM) findings in dogs with primary corneal squamous cell carcinoma (SCC).
Animals: Eight dogs with primary corneal SCC.
Procedures: Dogs diagnosed with primary corneal SCC by histopathology were examined with a modified Heidelberg Retina tomograph and Rostock Cornea Module prior to surgical intervention.
Eur J Ophthalmol
November 2024
Department of Ophthalmology, Adana City Training and Research Hospital, Adana, Turkiye.
Purpose: To investigate the discrimination ability of the corneal anterior and posterior surface area between patients with keratoconus stage 1 and normal individuals.
Methods: In this retrospective study, 116 eyes of 116 normal individuals and 366 eyes of 366 keratoconus patients were included. Keratoconus patients were divided into six groups according to the topographic keratoconus classification of Pentacam.
Mol Vis
July 2024
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD.
Purpose: While lacrimal gland removal is commonly used in animal models to replicate dry eye disease, research into systematically monitoring dry eye disease's longitudinal pathological changes is limited. In vivo confocal microscopy (Heidelberg Retina Tomograph 3 with a Rostock Cornea Module, Heidelberg Engineering Inc., Franklin, MA) can non-invasively reveal corneal histopathological structures.
View Article and Find Full Text PDFSci Rep
July 2024
Department of Ophthalmology, University of Pécs Medical School, Rákóczi U. 2, Pécs, 7623, Hungary.
To examine corneal subbasal nerve changes in patients who received vaccination against SARS-CoV-2 virus and underwent COVID-19 infection compared to infected non-vaccinated patients and healthy controls. Twenty-nine eyes of 29 vaccinated patients (mean age: 36.66 ± 12.
View Article and Find Full Text PDFCont Lens Anterior Eye
December 2024
Department of Ophthalmology, Mardin Training and Research Hospital, Mardin, Turkey. Electronic address:
Purpose: The purpose of the study was to demonstrate the feasibility of blink dynamics with a contactless, non-noticeable method without any visible light being reflected to the participant's eye by the device, and to investigate the blink dynamics parameters in 39 participants whose blink dynamics were examined with this method. It was also aimed to explain the potential of corneal topography devices for non-noticeable blink dynamics and elucidate some tips to device manufacturers to make them practical.
Methods: A one-minute real-time video image in the meibography module of the scheimpflug camera-based corneal topography device was recorded in the slow motion mode of the mobile phone.
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