Cross-coupling of benzylic acetates with arylboronic acids: one-pot transformation of benzylic alcohols to diarylmethanes.

Chem Commun (Camb)

Department of Chemistry, Graduate School of Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.

Published: December 2005

Benzylic acetates reacted with arylboronic acids in the presence of a DPEphos-[Pd(eta3-C3H5)Cl]2 catalyst when tert-amyl alcohol was used as a solvent, and the catalytic cross-couplings produced diarylmethanes in high yields (up to 94% isolated yield).

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Source
http://dx.doi.org/10.1039/b513372fDOI Listing

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