AI Article Synopsis
- A mix of hexamethyldisilane and deuterium oxide acts as a reagent to transfer deuterium into alkynes.
- In the presence of a small amount of a palladium complex, this reaction selectively produces (E)-1,2-dideuterioalkenes.
- The process goes through the intermediate (Z)-isomer before yielding the desired product.
Article Abstract
A combination of hexamethyldisilane and deuterium oxide was found to work as a deuterium transfer reagent for alkynes in the presence of a catalytic amount of a palladium complex to give (E)-1,2-dideuterioalkenes selectively through the corresponding (Z)-isomer.
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Article Synopsis
- A mix of hexamethyldisilane and deuterium oxide acts as a reagent to transfer deuterium into alkynes.
- In the presence of a small amount of a palladium complex, this reaction selectively produces (E)-1,2-dideuterioalkenes.
- The process goes through the intermediate (Z)-isomer before yielding the desired product.
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