Results from the elbow dysplasia screening program in Bernese Mountain Dogs of Germany were analysed in respect to its relevance for genetic evaluation and breeding. In total 2677 gradings were used. The grading was performed radiographically according to the recommendations of the International Elbow Working Group (IEWG). 75.8% of the dogs were free from visible dysplastic signs, 10.8%, 6.8% and 5.5% were classified to be of Grade 1, 2 and 3, respectively. 1.1% were classified as a borderline case between ED-free and Grade 1. A slight reduction of ED could be observed over years. Males had a 3.1 higher rate of dysplasia than females. Treating ED as a numerical trait, coded proportional to the severity of clinical relevant signs, gave a heritability estimation of 0.188 and a maternal effect of 0.07. From different mating combinations it was found, that ED average was higher in the progeny if one mate was affected but there was no increase in the prevalence with increasing grade of ED in the affected mates. About 10% more affected dogs could be observed, if one mate is affected. Heritability for dichotomic coding the trait was found to be 0.20. From these results can be suggested, that the differentiation in various grades of ED to describe the clinical relevance for the specific dog is helpfull, however, from a breeders point of view, dogs with ED should be treated equally for genetic evaluation.
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http://dx.doi.org/10.1024/0036-7281.147.11.491 | DOI Listing |
Vet Radiol Ultrasound
January 2025
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Medical image analysis based on deep learning is a rapidly advancing field in veterinary diagnostics. The aim of this retrospective diagnostic accuracy study was to develop and assess a convolutional neural network (CNN, EfficientNet) to evaluate elbow radiographs from dogs screened for elbow dysplasia. An auto-cropping tool based on the deep learning model RetinaNet was developed for radiograph preprocessing to crop the radiographs to the region of interest around the elbow joint.
View Article and Find Full Text PDFHeliyon
September 2024
Near East University, Faculty of Veterinary Medicine, Department of Surgery, Nicosia, Cyprus.
Canine hip and elbow dysplasias, which are prevalent orthopedic conditions rooted in developmental and hereditary factors are yet to be comprehensively assessed. This study aimed to address this gap by exploring the prognostic significance of five markers linked to canine hip dysplasia using available genome-wide association studies (GWAS) data. The influence of these markers on both hip and elbow dysplasia was examined in dogs exposed to standardized environmental conditions.
View Article and Find Full Text PDFVet Comp Orthop Traumatol
September 2024
AniCura Albano Small Animal Hospital, Danderyd, Sweden.
The aim of this study was to describe the physeal pathology of the proximal radius in four skeletally immature male Pugs. Physical examination, radiography, and computed tomography (CT) of the thoracic limbs were performed in all four dogs. Two Pugs were available for long-term follow-up and two Pugs were euthanatized after the diagnostic imaging results.
View Article and Find Full Text PDFAnimals (Basel)
September 2024
Center for Exceptional Longevity Studies, Gerald P. Murphy Cancer Foundation, West Lafayette, IN 47906, USA.
Emerging evidence in women supports the notion that pregnancy may reset disease resistance, thereby providing protection against subsequent adverse health outcomes, but this hypothesis has not been adequately explored in domestic dogs. Cranial cruciate ligament (CCL) rupture is a degenerative orthopedic disease that frequently affects pet dogs, and its risk has been associated with disruption of the reproductive hormone axis. Our research team is conducting a lifetime cohort study of purebred Rottweilers in North America that have lived 30% longer than breed-average.
View Article and Find Full Text PDFJ Orthop Case Rep
September 2024
Department of Orthopaedics, Sancheti Institute for Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
Introduction: Fibrous dysplasia (FD) is a skeletal developmental abnormality commonly affecting the ribs, femur, tibia, skull, pelvis, spine, and shoulder. FD of the proximal radius is extremely rare and very few cases have been reported. In addition, monostotic lesions of FD in the upper extremity go unnoticed as they are usually asymptomatic.
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