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Exploratory analysis of gait mechanics in farmers.
J Occup Environ Hyg
January 2025
Department of Kinesiology & Health Promotion, University of Kentucky, Lexington, Kentucky.
Farmers may be at a higher risk of developing hip osteoarthritis (OA) due to the high demands of their occupation. To the authors' knowledge, the gait patterns of farmers that may be associated with hip joint degeneration have yet to be analyzed. Therefore, this study compares gait mechanics between farmers and non-farmers (controls).
View Article and Find Full Text PDFA morphometric study of posterior tibial slope differences by sex and ethnicity in a South African population.
Surg Radiol Anat
January 2025
University of Pretoria, Pretoria, South Africa.
Purpose: Posterior tibial slope (PTS) influences knee kinetics and kinematics. The purpose of this study was to investigate morphology and variation within a sample of the black and white male and female population.
Method: 480 randomly selected lateral knee radiographs were included.
Exposure of Young Mice to Atmospherically Relevant PM Has Sex-Dependent Long-Lasting Impacts on the Skeletal Muscle System.
Aging Dis
December 2024
Department of Sports Science, College of Natural Science, Jeonbuk National University, Jeonju 54896, Korea.
The negative effects of particulate matter up to 2.5 μm in diameter (PM) and their mediating mechanisms have been studied in various tissues. However, little is known about the mechanism and long-term tracking underlying the sex-dependent effects of PM on skeletal muscle system modulation.
View Article and Find Full Text PDFPopulation Pharmacokinetics and Pharmacodynamics of Sotalol Following Expedited Intravenous Loading in Patients With Atrial Arrhythmias.
CPT Pharmacometrics Syst Pharmacol
January 2025
Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Sotalol, a class III antiarrhythmic agent, is used to maintain sinus rhythm in patients with atrial fibrillation or atrial flutter (AFIB/AFL). Despite its efficacy, sotalol's use is limited by its potential to cause life-threatening ventricular arrhythmias due to QT interval prolongation. Traditionally, sotalol administration required hospitalization to monitor these risks.
View Article and Find Full Text PDFSex differences in cardiac energetics in the rat ventricular muscle.
Sci Rep
December 2024
Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
Cardiac sex-difference functional studies have centred on measurements of twitch force and Ca dynamics. The energy expenditures from these two cellular processes: activation (Ca handling) and contraction (cross-bridge cycling), have not been assessed, and compared, between sexes. Whole-heart studies measuring oxygen consumption do not directly measure the energy expenditure of these activation-contraction processes.
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