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Anal Biochem
September 2010
Department of Chemistry, Aleppo University, Syria.
Anal Sci
September 2007
Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt.
Two simple, precise, inexpensive and sensitive voltammetric methods for the determination of lomefloxacin (LFX), sparfloxacin hydrochloride (SFX), gatifloxacin (GFX), and moxifloxacin (MFX) were developed. The present methods were first used to explore the adsorption behavior of the four investigated antibacterial agents at a hanging mercury dropping electrode (HMDE), by a direct method and secondly by a modification via their complexation with PdCl(2). For the direct method, drugs were accumulated on HMDE, and a well-defined reduction peak was obtained in Britton-Robinson buffer of pH 7 for LFX and SFX, and pH 6 for GFX and MFX.
View Article and Find Full Text PDFJ Hazard Mater
July 2005
Dipartimento di Chimica, Università La Sapienza, Rome, Italy.
The electrochemical behaviour of acidic and neutral pharmaceutical active compounds (PhACs) was studied by cyclic voltammetry and pulse voltammetric techniques on mercury, carbon nanotube paste, carbon paste and gold electrodes. The best results, in terms of sensitivity, linearity range and detection limits, were obtained by differential pulse voltammetry (DPV) for ofloxacin (LOD 5.2 microM), differential pulse polarography (DPP) for clofibric acid (LOD 4.
View Article and Find Full Text PDFJ Inorg Biochem
February 2005
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Askerceva 5, SI-1000 Ljubljana, Slovenia.
A new quinolone-metal complex was prepared by a hydrothermal reaction in the presence of L-histidine that served as a reducing agent for a metal. The title compound [Cu(II)(cfH)(2)(Cu(I)Cl(2))(2)] (1) is a mixed-valence Cu(II)-Cu(I) complex, which contains two ciprofloxacin (cfH) molecules bonded to the central copper(II) atom and two almost planar [Cu(I)Cl(2)](-) moieties. Both metal centers are connected through two bridging atoms (chloride and quinolone oxygen).
View Article and Find Full Text PDFAnal Bioanal Chem
March 2004
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100, Ankara, Turkey.
The oxidative behaviour of moxifloxacin was studied at a glassy carbon electrode in different buffer systems using cyclic, differential pulse, and Osteryoung square-wave voltammetry. The oxidation process was shown to be irreversible over the entire pH range studied (2.0-10.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!