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Systemic T17 infection in a free-ranging two-toed sloth: case report and literature review of infections by free-living amebas in mammals.
J Vet Diagn Invest
October 2024
California Animal Health and Food Safety Laboratory System, University of California-Davis, San Bernardino, CA, USA.
A free-ranging, adult female two-toed sloth () was brought to a wildlife rescue center in Costa Rica with ocular and auricular myiasis and numerous skin lesions. After one month of unsuccessful systemic and topical antimicrobial treatment, the patient died. A postmortem examination was performed, and tissues were examined histologically, confirming disseminated amebic infection with intralesional trophozoites and cysts in the lungs, liver, eye, heart, spleen, and stomach.
View Article and Find Full Text PDFDiversity of Free-Living Amoebae in New Zealand Groundwater and Their Ability to Feed on .
Pathogens
August 2024
Institute of Environmental Science and Research, 27 Creyke Road, Ilam, Christchurch 8041, New Zealand.
Free-living amoebae (FLA) are common in both natural and engineered freshwater ecosystems. They play important roles in biofilm control and contaminant removal through the predation of bacteria and other taxa. Bacterial predation by FLA is also thought to contribute to pathogen dispersal and infectious disease transmission in freshwater environments via the egestion of viable bacteria.
View Article and Find Full Text PDFA double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthamoeba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) study.
Trials
August 2024
Francis I. Proctor Foundation, University of California, Sao Paulo, Brazil.
Background: Infectious keratitis secondary to fungus or acanthamoeba often has a poor outcome despite receiving the best available medical therapy. In vitro rose bengal photodynamic therapy (RB-PDT) appears to be effective against fungal and acanthamoeba isolates (Atalay HT et al., Curr Eye Res 43:1322-5, 2018, Arboleda A et al.
View Article and Find Full Text PDFBackground: Infectious keratitis secondary to fungus or acanthamoeba often has a poor outcome despite receiving the best available medical therapy. Rose Bengal Photodynamic therapy (RB-PDT) appears to be effective against fungal and acanthamoeba isolates. In one published series RB-PDT reduced the need for therapeutic penetrating keratoplasty in severe bacterial, fungal, and acanthameoba keratitis not responsive to medical therapy.
View Article and Find Full Text PDFDisseminated infection in a patient with AIDS: a case report and literature review.
Front Med (Lausanne)
June 2024
Department of Infectious Disease, Zhongnan Hospital of Wuhan University, Wuhan, China.
Background: infection is a rare condition primarily occurring in immunocompromised patients with extremely high mortality. Currently, there is no standard treatment for this condition, and successful treatment reports are scarce.
Case Presentation: We present a case of infection in a 63-year-old female patient with AIDS, who was admitted to our hospital with symptoms of fever, skin ulcers, subcutaneous nodules, and food regurgitation from the nose while eating.
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