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Review of Applications of Microneedling in Melasma.
J Cosmet Dermatol
January 2025
Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, China.
Background: Melasma, a common skin pigmentation disease, can negatively impact patients' mental health, social interactions, and physical appearance. Although we now have several treatments accessible, such as medicines, chemical peels, and phototherapy, which can help ease symptoms to some extent, the requirement for a long-term effective and safe treatment for patients is far from met. In the face of this problem, microneedling, as an innovative treatment, provides a new avenue for treating melasma.
View Article and Find Full Text PDF#Opioids: A Mixed Methods Examination of Top Opioid-Related Content on TikTok.
J Stud Alcohol Drugs
December 2024
Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI.
Objective: Despite an abundance of public discourse about the opioid crisis in the media, there is little research characterizing opioid-related content on TikTok, a popular video-based social media platform. This study sought to examine how opioids are portrayed on TikTok.
Methods: This study used mixed-methods to analyze top opioid-related posts marked with the hashtag "#opioids" collected in May 2023.
A Rare Case of Corneal Perforation Secondary to Gonococcal Keratoconjunctivitis.
Cureus
November 2024
Ophthalmology, Universiti Sains Malaysia, Kota Bharu, MYS.
Gonococcal keratoconjunctivitis (GKC) is an aggressive infection caused by , which can cause an acute, dreadful, ulcerative keratitis resulting in blindness if left untreated. We report a rare case of bilateral GKC complicated with left eye corneal perforation. A 20-year-old male presented with bilateral eye purulent discharge associated with vision loss over the left eye for two weeks prior to presentation.
View Article and Find Full Text PDFGene editing tool-loaded biomimetic cationic vesicles with highly efficient bacterial internalization for in vivo eradication of pathogens.
J Nanobiotechnology
December 2024
Beijing Institute of Radiation Medicine, 27 Taiping Road, Beijing, 100850, China.
In the post-COVID-19 era, drug-resistant bacterial infections emerge as one of major death causes, where multidrug-resistant Acinetobacter baumannii (MRAB) and drug-resistant Pseudomonas aeruginosa (DRPA) represent primary pathogens. However, the classical antibiotic strategy currently faces the bottleneck of drug resistance. We develop an antimicrobial strategy that applies the selective delivery of CRISPR/Cas9 plasmids to pathogens with biomimetic cationic hybrid vesicles (BCVs), irrelevant to bacterial drug resistance.
View Article and Find Full Text PDFAnalysis of topical conjunctival microbiotic cultures in patients treated with intravitreal injections using antibiotic prophylaxis with 0.3% ofloxacin eye drops.
Int J Retina Vitreous
December 2024
Centro Universitário Faculdade de Medicina Do ABC/FMABC, Santo André, Brazil.
Background: Intravitreal injections, a relatively recent treatment in ophthalmology, is being adopted rapidly worldwide and becoming one of the most common therapies in the field. Numerous complications are associated with this treatment, ranging from minor inflammatory ailments to endophthalmitis. We analyzed the conjunctival flora of patients treated with intravitreal injections and topical antibiotics.
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