A 59-year-old man was admitted with giant tumor of testis and massive hemorrhage into accompanying hydrocele. His clinical status had become worse quickly. The emergency resection of tumor with hematocele was performed. The diagnosis was made upon histological examination of the postoperative tissue and was confirmed by immunohistochemistry. Spermatocytic seminoma was recognized. The surgical specimen comprised a tumor (26 cm x 28 cm x 17 cm) in size, weighed 2150 g. Tumor with hematocele achieved about 40 cm in diameter.
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http://dx.doi.org/10.1007/s11255-005-2085-0 | DOI Listing |
Sci Rep
December 2024
Clinical Molecular Genetics and Epigenetics, Faculty of Health, Centre for Biomedical Education & Research (ZBAF), Witten/Herdecke University, Alfred-Herrhausen-Str. 50, 58448, Witten, Germany.
Testicular cell differentiation is a highly regulated process, essential for male reproductive health. The histone variant H3.5 is apparently a critical player in this intricate orchestra of cell types, but its regulation and function remains poorly understood.
View Article and Find Full Text PDFUrol Case Rep
July 2024
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Spermatocytic tumors are rare testicular cancers, accounting for less than 1 % of all testicular neoplasms, usually affecting older men. This report details a 35-year-old male with a spermatocytic tumor featuring extensive lymphovascular invasion. The patient had a painless, slow-growing right testicular mass, with normal serum tumor markers.
View Article and Find Full Text PDFHistopathology
November 2024
Institute of Pathology, University Medical Center, Göttingen, Germany.
Hum Pathol
June 2024
Department of Pathology Indiana University, Indianapolis, IN, USA. Electronic address:
Spermatocytic tumors are rare testicular tumors occurring predominantly in older men. Most show a classical tripartite morphology (different from seminoma) and are benign. However, well-documented cases of malignant spermatocytic tumors exist.
View Article and Find Full Text PDFBiol Reprod
August 2024
Epivara, Inc., 2109 S. Oak Street, Suite 100A, Champaign, IL 61820, USA.
Cryptorchidism, the failure of one or both testes to descend into the scrotum, and testicular cancer show a strong correlation in both dogs and humans. Yet, long-standing medical debates persist about whether the location of undescended testes directly causes testicular cancer in humans or if both conditions stem from a common origin. Although testicular cancer is a prevalent disease in dogs, even less is known about its cause and correlation with testicular descent in this species.
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