Download full-text PDF

Source
http://dx.doi.org/10.2174/156720105774370276DOI Listing

Publication Analysis

Top Keywords

lipid-based nanosystems
4
nanosystems complexes
4
complexes experimental
4
experimental clinical
4
clinical therapeutics
4
lipid-based
1
complexes
1
experimental
1
clinical
1
therapeutics
1

Similar Publications

Gold nanoparticles decorated FOLFIRINOX loaded liposomes for synergistic therapy of pancreatic cancer.

Int J Pharm

December 2024

Department of Bioengineering, Graduate School of Science and Engineering, Hacettepe University, 06800 Beytepe, Ankara, Turkey; Department of Chemical Engineering, Faculty of Engineering, Hacettepe University, Ankara, 06800, Turkey. Electronic address:

Pancreatic cancer is predicted to be the second highest cause of cancer deaths by 2030, with a mortality rate of 98 % and a 5-year survival rate of only 4-8 %. FOLFIRINOX which consists of four main ingredients has shown superior efficacy in treating patients with pancreatic cancer compared to other agents and combinations. However, toxicities have prevented full-dose use of FOLFIRINOX.

View Article and Find Full Text PDF

Improving antifungal lipid-based drug delivery against : a review.

Expert Opin Drug Deliv

October 2024

Department of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.

Introduction: Fungal infections, particularly those caused by spp. have increased in recent years. A primary contributor to this surge was the COVID-19 pandemic, where many hospitalized patients had secondary fungal infections.

View Article and Find Full Text PDF

Cancer, a complex global health burden, necessitates the development of innovative therapeutic strategies. While chemotherapy remains the primary treatment approach, its severe side effects and chemoresistance drive the search for novel alternatives. Essential oils (EOs), consisting of diverse bioactive phytochemicals, offer promise as anticancer agents.

View Article and Find Full Text PDF

MRI detection of free-contrast agent nanoparticles.

Magn Reson Med

February 2025

Molecular and Preclinical Imaging Centers, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.

Article Synopsis
  • The research explores a new way to visualize nanoparticles in medical imaging using MRI and MRS techniques, specifically focusing on detecting natural proton signals in commonly used nanosystems.
  • Three different nanosystems (lipid-based micelles, liposomes, and perfluorocarbon-based nanoemulsions) were created and characterized, with the perfluorocarbon-based nanoemulsion showing the best performance in signal detection.
  • This method allows for the detection of nanoparticles without needing additional probes, indicating a significant advancement in non-invasive imaging for diagnostics and treatments in biomedical applications.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!