Efficacy of caspofungin against Aspergillus terreus.

Antimicrob Agents Chemother

Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria, Ospedali Riuniti Umberto I-Lancisi-Salesi, Via Conca, Torrette, Ancona 60020, Italy.

Published: December 2005

We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315968PMC
http://dx.doi.org/10.1128/AAC.49.12.5133-5135.2005DOI Listing

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