Aim: The study determined the effects of packaging solution osmolality and buffering agent on soft contact lens parameters.
Methods: One lens type from each FDA contact lens material category was equilibrated to phosphate buffered saline (PBS) or borate buffered saline (BBS), at three osmolality concentrations: 270, 310 and 414 mOsmol/kg. Lens diameter (LD), base curve (BOZR) and back vertex power (BVP) were measured and compared to nominal packaging label values.
Results: Statistically significant differences were found in all three parameters across all osmolality levels for both buffering agents. Etafilcon A showed the largest amount of parameter change, followed by alphafilcon A and balafilcon A. Lotrafilcon A was the least affected. LD of alphafilcon A lenses (greater than +/- 0.2 mm) and BVP of lotrafilcon A and etafilcon A lenses (greater than +/- 0.25 D) measured outside the International Standards Organization (ISO) tolerance from their packaging labels when measured in solutions that mimicked their packaging solutions.
Conclusion: Osmolality and buffering agents influence lens parameters. Packaging solutions can vary the parameters of some lens types from their nominal value to outside the tolerance range set by ISO.
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| http://dx.doi.org/10.1016/j.clae.2003.11.002 | DOI Listing |
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