Measurement of corneal thickness has potential benefit both in the fitting of contact lenses and in monitoring any pathology that could affect corneal thickness. Corneal thickness measurement is undertaken using an accessory to the biomicroscope, the optical pachometer, or by means of expensive apparatus such as the ultrasonic pachometer. There are other complex methods, such as laser Doppler interferometry, or ultrasonic rasters of the cornea. In this study, an easier and low cost method, based on the measurement of the optical section formed of the cornea by the biomicroscope illumination system, is proposed. The advantages of this new method are the simplicity of its experimental set-up which consists of a calibrated graticule in an eyepiece of the biomicroscope, the speed of the measurement which increases with practice and the low cost, due to the fact that the biomicroscope is standard equipment in the ophthalmic consulting room.
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http://dx.doi.org/10.1016/s1367-0484(98)80004-0 | DOI Listing |
Klin Monbl Augenheilkd
January 2025
Ophthalmology, Talacker Eye Center Zurich (TAZZ), Switzerland.
Background: Nineteen-year follow-up after initial examination on patients with Axenfeld-Rieger anomaly or syndrome (ARAS) and coexisting Fuchs' endothelial dystrophy (FED). All individuals had previously been tested positive for the PITX2 (g.20 913 G>T) mutation.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
GROW Research Laboratory, Narayana Netralaya Foundation, Bangalore, India.
Purpose: Keratoconus (KC) is characterized by irregular astigmatism along with corneal stromal weakness and is associated with altered immune status. Tissue resident microbiomes are known to influence the immune status in other organs, but such a nexus has not been described in ocular conditions. Therefore, we examined the ocular surface microbiome of patients with KC and correlated it to the immune cell and tear molecular factor profiles.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Purpose: Descemet membrane endothelial keratoplasty (DMEK) has emerged as a novel approach in corneal transplantation over the past two decades. This study aims to identify predisposing risk factors for post-DMEK ocular hypertension (OHT) and develop a preoperative predictive model for post-DMEK OHT.
Methods: Patients who underwent DMEK at Gangnam Severance Hospital between 2017 and 2024 were included in the study.
ACS Biomater Sci Eng
January 2025
Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Effective storage and utilization of limited donor corneal resources are in high demand to alleviate the shortage of donor corneal tissue. Here, we designed a static air-lifted organ culture system equipped with a protective coverage membrane, namely, an air-lifted OC-P system, to provide a biomimetic physiological environment for full-thickness corneal preservation. The air-lifted OC-P system features a unique collagen-based protective coverage membrane that can offer a moist, oxygen-rich environment for corneal epithelium, produce an appropriate intraocular pressure onto the cornea by gravity, and facilitate the maintenance of the organ culture medium level for nutrient supply during corneal preservation.
View Article and Find Full Text PDFClin Ophthalmol
January 2025
Department of Ophthalmology, Manhattan Eye, Ear, and Throat Hospital/Northwell Health, New York, NY, USA.
Purpose: To assess the diagnostic capability of pattern electroretinography (PERG) and varying circumpapillary optical coherence tomography (OCT) scan diameters in glaucoma suspects (GS).
Methods: This is a prospective, cross-sectional study. Circumpapillary retinal nerve fiber layer thickness (RNFLT) was measured using spectral domain OCT in 49 eyes from 26 patients (36 normal, 13 GS) in three circle diameters (3.
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