The purpose of this study was to compare the effect of manual and mechanical instrumentation techniques in curved root canals using area of dentine removed and canal axis movement as the end-points. Sixty mandibular molars with curved root canals with angulations ranging from 15 degrees to 45 degrees were selected. The teeth were embedded in transparent resin in a grilon key-like muffle using Bramante's procedure. The roots were horizontally sectioned at three levels and pre and post instrumentation photographs were taken. The sections were reassembled in the muffle and the canals were instrumented with manual and mechanical techniques using Cursor (W&H). Anatomic measurements of transportation were made employing pre and post instrumentation photographs and Macintosh Image 1.45 Software. Statistical analysis of the data was performed by ANOVA. There were no significant differences in canal center axis movement among the groups. Differences in area of dentine removed between manual and mechanical instrumentation techniques were observed at the apical level only.
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PLoS One
January 2025
School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
The incidence of acute myeloid leukemia (AML) is increasing annually, and timely diagnostic and treatments can substantially improve patient survival rates. AML typing traditionally relies on manual microscopy for classifying and counting myeloid cells, which is time-consuming, laborious, and subjective. Therefore, developing a reliable automated model for myeloid cell classification is imperative.
View Article and Find Full Text PDFJ Vis Exp
January 2025
School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine;
The therapeutic effectiveness of acupuncture relies on both safety and stability, making these factors essential in acupuncture manipulation research. However, manual manipulation introduces unavoidable inaccuracies, which can impact the reliability of research findings. To address this challenge, a unique lifting and thrusting manipulation control cannula was designed in this study, offering flexible adjustment of movement amplitude.
View Article and Find Full Text PDFBiosens Bioelectron
January 2025
Anhui Institute of Optics and Fine Mechanics, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China. Electronic address:
Pathogen nucleic acid detection technology based on isothermal amplification and CRISPR/Cas12a system offers advantages in terms of high sensitivity, high specificity, and rapidity. However, this method has not been widely applied because of its shortcomings in utilizing conventional instruments, which cannot satisfy the requirements for Point of Care Testing (POCT), such as integration, convenience, and miniaturization. In this study, we developed an integrated lift-heater centrifugal microfluidic platform (Lift-CM) to automate the processes of isothermal amplification and CRISPR/Cas12a detection.
View Article and Find Full Text PDFJ Prosthodont
January 2025
Division of Oral Surgery and Implantology, Department of Head and Neck, Institute of Clinical Dentistry, Oral Surgery and Implantology Unit, A. Gemelli University Hospital Foundation (IRCCS) Catholic University of the Sacred Heart, Rome, Italy.
Purpose: Screw-retained implant crowns are a common solution to rehabilitate single or multiple edentulous sites. Angulated screw channel (ASC) abutments have been developed as a new system of connection to correct the angulation of the implant and avoid a possible undesired emergence of the access hole. The purpose of this systematic review was to examine available literature related to the effects of ASC abutments in rehabilitating single implant crowns.
View Article and Find Full Text PDFSci Rep
January 2025
Emergency Department, The State Key Laboratory for Complex, Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Variation in the incidence, survival rate and factors associated with survival after cardiac arrest in China is reported. Some studies have tried to fill the knowledge gap regarding the epidemiology of cardiac arrest in China but were unable to identify reasons for the reported differences. Therefore, the purpose of this study was to describe Chinese management of cardiac arrest, particularly from the perspective of compression, ventilation, monitoring, treatment, and extracorporeal cardiopulmonary resuscitation.
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