In the past 20 years, there has been increasing recognition that for some women, pregnancy may be burdened with mood problems, in particular depression, that may impact both mother and child. With identification of risk factors for postpartum depression and a growing knowledge about a biologic vulnerability for mood change following delivery, research has accumulated on attempts to prevent postpartum depression using various psychosocial, psychopharmacologic, and hormonal strategies. The majority of psychosocial and hormonal strategies have shown little effect on postpartum depression. Notwithstanding, results from preliminary trials of interpersonal therapy, cognitive-behavioural therapy, and antidepressants indicate that these strategies may be of benefit. Information on prevention of postpartum depression using dietary supplements is sparse and the available evidence is inconclusive. Although a few studies show promising results, more rigorous trials are required. The abounding negative evidence in the literature indicates that postpartum depression cannot be easily prevented, yet.
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http://dx.doi.org/10.1590/s1516-44462005000600005 | DOI Listing |
Obstet Gynecol Clin North Am
March 2025
Department of Obstetrics Gynecology, University of South Florida, Tampa, FL, USA.
Maternal mortality has increased over past decades. The majority of deaths are secondary to mental health and substance use disorders, with over 80% being preventable. Screening for mental health should be offered to all pregnant women and should be administered through all trimesters and postpartum.
View Article and Find Full Text PDFObstet Gynecol Clin North Am
March 2025
Department of Obstetrics and Gynecology, Montefiore Albert Einstein College of Medicine. Electronic address:
This is a review of the existing literature and guidelines for the screening, management, and follow-up of perinatal mood and anxiety disorders, with a focus on major depressive disorder and generalized anxiety disorder.
View Article and Find Full Text PDFGinekol Pol
January 2025
Department of Neonatology and Rare Diseases, Faculty of Health Sciences, Medical University of Warsaw, Poland.
Objectives: Postpartum depression is a common and serious mental health problem which is associated with maternal distress and negative consequences for the offspring. Research confirms the presence of differences in the prevalence of postpartum depression in different social groups. The aim of this study was to compare the severity of maternal symptoms in Poland and Zimbabwe and to identify risk factors occurring in both groups.
View Article and Find Full Text PDFNeurobiol Stress
January 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Postpartum depression (PPD) adversely affects the growth and development of the offspring, increasing the risk of various internalizing behaviorsduring adolescence. Studies have shown that corticosterone (CORT)-induced PPD affects neurogenesis in the offspring, which is closely related to the onset of depression. However, the underlying mechanisms of these changes in the offspring of PPD mothers remain unexplored.
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