AI Article Synopsis
- A report details a malignant embryonal tumor in a 6-month-old Brahman crossbred calf, specifically a primitive neuroectodermal tumor at the lumbosacral junction.
- The tumor consisted of spindloid embryonal cells with distinctive nuclear characteristics and minimal cytoplasm.
- Immunohistochemical staining indicated potential neuronal and ependymal differentiation through markers such as neuron-specific enolase and synaptophysin.
Article Abstract
A variety of embryonal tumors of the central nervous system, typically malignant and occurring in young individuals, are recognized in humans and animals. This report describes an invasive subdural but predominantly extramedullary primitive neuroectodermal tumor developing at the lumbosacral junction in a 6-month-old Brahman crossbred calf. The tumor was composed of spindloid embryonal cells organized in interlacing fascicles. The cells had oval to elongate or round hyperchromic nuclei, single to double nucleoli, and scant discernible cytoplasm. Immunohistochemical staining for neuron-specific enolase, synaptophysin, and S-100 protein and formation of pseudorosettes suggested neuronal and possibly ependymal differentiation.
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| http://dx.doi.org/10.1354/vp.42-6-834 | DOI Listing |
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