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Diabetes-Related Extremity Amputation Depression and Distress (DREADD): A Multimethod Study.
Semin Vasc Surg
March 2025
Keck School of Medicine of USC, Los Angeles, CA.
Of the roughly 38 million people diagnosed with type 2 diabetes mellitus in the United States, up to 34% will develop a diabetic foot ulcer at some point, up to 75% of those who develop an ulcer will experience recurrent ulcers, and approximately 18% of patients with a diabetic foot ulcer will undergo lower-limb amputation. The aim of this study was to determine whether depressive symptoms change after a minor, nontraumatic amputation. We conducted a multimethod study consisting of semi-structured interviews (n = 12) and a retrospective cohort (n = 20) of patients with type 2 diabetes mellitus who underwent a nontraumatic, minor amputation of a single toe (partial or total) or partial ray resection.
View Article and Find Full Text PDFBest practice offloading treatments for diabetic foot ulcer healing, remission, and better plans for the healing-remission transition.
Semin Vasc Surg
March 2025
Australian Centre for Health Services Innovation & Centre for Healthcare Transformation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia; Department of Rehabilitation Medicine, Amsterdam Movement Sciences,Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Diabetes-related foot disease is arguably the world's least known major health problem and causes a disease burden larger than most well-known diseases, such as stroke and breast cancer. This burden is driven by people developing more severe stages of foot disease, such as foot ulcers and infections, and with that worsening quality of life. To reduce this burden, we need treatments that prevent more severe stages of foot disease and improve quality of life.
View Article and Find Full Text PDFAnaphylactic shock is a severe, potentially life-threatening systemic allergic reaction. It can involve multiple organ systems and is triggered by medication, food, or insect stings. Epidemiological data vary due to differing definitions, but studies estimate that 0,26% of hospital admissions are due to anaphylaxis, with 1-3 deaths per million annually.
View Article and Find Full Text PDFPostmenopausal endometriosis.
BMJ Case Rep
March 2025
Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia
A postmenopausal woman, in her 60s, married with no history of pregnancy, presented to our facility with an abdominal mass of 2 months duration that progressively increased in size. Physical examination revealed a mobile abdominal cystic mass measuring approximately 20×20×10 cm, accompanied by ascites. Transvaginal ultrasonography showed a hypoechoic cystic mass measured >14.
View Article and Find Full Text PDFSebaceous carcinoma presenting as chronic chalazion.
BMJ Case Rep
March 2025
Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
We present a case of sebaceous carcinoma presenting as treatment-resistant chalazion. Diagnosis was made by excisional biopsy after failed treatment with warm compresses, eyelid hygiene and erythromycin ointment. Conjunctival map biopsies excluded local spread.
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