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Anti-PD1-/PDL1-induced chronic intestinal pseudo-obstruction: three cases treated with vedolizumab after corticosteroid failure with mixed results.
Cancer Immunol Immunother
January 2025
Department of Medical Oncology, Institut de Cancérologie de L'Ouest, 44805, Saint Herblain, France.
Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers.
View Article and Find Full Text PDFVisible Peristalsis in a Patient Referred for Chronic Intestinal Pseudo-Obstruction.
Am J Gastroenterol
January 2025
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Protein-losing enteropathy as the first presentation of systemic lupus erythematosus the first case reported in Palestine with systemic review.
Ann Med Surg (Lond)
December 2024
Al- Ahli Hospital, Department of Internal Medicine, Hebron, State of Palestine.
Introduction: Systemic lupus erythematosus is a chronic inflammatory disease affecting women, causing gastrointestinal issues like acute pancreatitis, esophagitis, and protein-losing enteropathy. Protein loss is uncommon, but a case study shows protein-losing enteropathy as a first sign.
Importance: Protein-losing enteropathy (PLE) is a rare gastrointestinal manifestation of SLE, often seen years before diagnosis.
Resolution of dysphagia due to secondary achalasia with neuropathic chronic intestinal pseudo-obstruction by peroral endoscopic myotomy.
Rev Esp Enferm Dig
December 2024
Gastroenterology, Hospital Universitario de La Princesa.
Chronic intestinal pseudo-obstruction (CIPO) is a rare condition affecting the motility of the lower gastrointestinal tract, while achalasia is an uncommon esophageal motility disorder. The coexistence of both conditions is extremely rare. We present the case of a patient who had both pathologies, admitted for dysphagia and oral intolerance, the symptoms finally resolved by performing a POEM.
View Article and Find Full Text PDFEffective Management of Chronic Intestinal Pseudo-Obstruction in MELAS Using Acotiamide: A Case Report.
Case Rep Neurol
September 2024
Department of Neurology, Graduate School of Medicine, Mie University, Tsu, Japan.
Article Synopsis
- * A 51-year-old woman with MELAS experienced symptoms of CIPO, including nausea and abdominal distension, after treatment for a stroke-like episode; imaging showed intestinal dilatation without obstruction.
- * Acotiamide, a medication that enhances gastrointestinal motility by inhibiting acetylcholinesterase, improved her CIPO symptoms, suggesting its potential role in treating such patients.
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