AI Article Synopsis
- Two bodybuilders, previously healthy, experienced sudden cardiac death (SCD) linked to chronic use of androgenic-anabolic steroids.
- Autopsies and toxicology tests were conducted on both cases, revealing concerning findings.
- The study suggests that intense weight training plus steroid use and increased sensitivity to androgens may significantly heighten the risk of heart injury and SCD in young men.
Article Abstract
We report two cases of sudden cardiac death (SCD) involving previously healthy bodybuilders who were chronic androgenic-anabolic steroids users. In both instances, autopsies, histology of the organs, and toxicologic screening were performed. Our findings support an emerging consensus that the effects of vigorous weight training, combined with anabolic steroid use and increased androgen sensitivity, may predispose these young men to myocardial injury and even SCD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00414-005-0055-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integration of Rapid Cycle Deliberate Practice Into Prelicensure Nursing Curricula: Preparing Nursing Students for Cardiac Arrest Care.
Nurse Educ
January 2025
Authors Affiliations: Department of Biobehavioral Nursing Science (Drs Castro, Stephens, and Vanderzwan), Department of Human Development Nursing Science (Ms Ortiz), College of Nursing, University of Illinois at Chicago, Chicago, IL.
Background: Nursing students are not consistently trained on how to care for patients experiencing sudden cardiac arrest. In rapid cycle deliberate practice (RCDP), learners perform a simulation with micro-debriefs interjected by the instructor.
Problem: RCDP has been used to train health care students on how to respond during a sudden cardiac arrest, but its application to prelicensure nursing students is underreported.
A new HCM heart sound classification method based on weighted bispectrum features.
Phys Eng Sci Med
January 2025
School of Electrical Engineering and Electronic Information, Xihua University, Chengdu, China.
Hypertrophic cardiomyopathy (HCM), including obstructive HCM and non-obstructive HCM, can lead to sudden cardiac arrest in adolescents and athletes. Early diagnosis and treatment through auscultation of different types of HCM can prevent the occurrence of malignant events. However, it is challenging to distinguish the pathological information of HCM related to differential left ventricular outflow tract pressure gradients.
View Article and Find Full Text PDFCardiac sarcoidosis; update for the heart failure specialist.
Curr Opin Cardiol
January 2025
Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa, Faculty of Medicine, Tier 1 Clinical Research Chair in Cardiac Electrophysiology, Ottawa, ON, Canada.
Purpose Of Review: This review presents contemporary data on epidemiology, common presentations, investigations and diagnostic algorithms, treatment and prognosis. It particularly focuses on topics of most relevance to heart failure specialists, including what left ventricle (LV) function changes can be expected after treatment and outcomes to all standard and advanced heart failure therapies.
Recent Findings: Around 5% of sarcoidosis patients have clinically manifest cardiac sarcoidosis (CS), presenting with significant arrhythmias (such as conduction disturbances and ventricular arrhythmias) or newly developed unexplained heart failure.
Comparative efficacy of single-coil versus dual-coil ICD leads: a meta-analysis of clinical outcomes.
Future Cardiol
January 2025
Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Background: Implantable cardioverter-defibrillators (ICDs) are essential for reducing sudden cardiac death in patients at risk of ventricular arrhythmias. The choice of ICD lead - single-coil or dual-coil - can influence device performance and patient outcomes. This meta-analysis evaluates the comparative efficacy and safety of single-coil versus dual-coil ICD leads to inform clinical decision-making.
View Article and Find Full Text PDFPPA2-associated cardiac arrest survivor.
Cardiol Young
January 2025
Royal Belfast Hospital for Sick Children, Belfast, UK.
Biallelic pathogenic variants in the inorganic pyrophosphatase 2 (PPA2) gene are a rare but established cause of sudden infant death, which may be precipitated by a pyrexial or viral illness. It has also been associated with sudden death secondary to alcohol ingestion in young adults. We describe the case of a thirteen-month-old female who presented following out-of- hospital cardiac arrest and was subsequently diagnosed with compound, heterozygous pathogenic variants of PPA2.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!