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- Patients awaiting heart transplants often require colonoscopies due to bleeding or screening needs, but there's limited research on the safety of these procedures for individuals on inotropic medications or mechanical circulatory support.
- A study was conducted from 2015 to 2021 with 92 heart failure patients undergoing colonoscopy while on advanced heart failure therapies, such as inotropes or mechanical devices.
- Results indicated that the most common reason for colonoscopy was cancer screening, with significant findings including 8% of screening procedures revealing advanced adenomas and 17% of bleeding-related colonoscopies identifying sources needing intervention, but no major complications related to anesthesia were reported.
Levosimendan, a Promising Pharmacotherapy in Cardiogenic Shock: A Comprehensive Review.
Eur Cardiol
November 2024
National Heart and Lung Institute, Faculty of Medicine, Imperial College London London, UK.
Cardiogenic shock (CS) is a critical condition with high mortality rate, as the current management of CS presents significant challenges. Exploration of more effective therapies is necessitated. This review article comprehensively examines the efficacy and safety of levosimendan in the management of CS.
View Article and Find Full Text PDFSafety of dobutamine stress cardiovascular magnetic resonance in patients with prior coronary artery bypass grafting.
J Cardiovasc Magn Reson
December 2024
Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany; MEDNEO, Hamburg, Germany.
Article Synopsis
- Patients with coronary artery bypass grafts (CABG) are at higher risk for serious heart issues, and this study investigates the safety of high-dose dobutamine stress cardiovascular magnetic resonance (DCMR) imaging for these patients.
- A total of 336 CABG patients were reviewed, noting adverse events and symptoms during DCMR compared to a control group of 200 individuals without CABG.
- The findings revealed similar rates of adverse events and aborted DCMR examinations between CABG patients and controls, suggesting that DCMR may be safely performed in patients with CABG.
Enteral Nutrition in Neonates on Inotropic Support Admitted to a Tertiary Neonatal Intensive Care Unit: A Prospective Cohort Study.
Cureus
September 2024
Pediatrics, Shri B. M. Patil Medical College Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, IND.
Background Early initiation of enteral feeding in neonates on inotropic support may improve clinical outcomes compared to intravenous fluids, but the safety and optimal inotrope levels for enteral nutrition remain unclear. This study aims to assess the early initiation of enteral feeding versus intravenous fluids in newborns on inotrope support and to compare the clinical outcome in terms of hospital stay, morbidity, and mortality in neonates with enteral feed versus intravenous (IV) fluid group on inotropes. It also focuses on evaluating the safety of enteral nutrition in neonates with inotropic support and determining the cutoff levels of the inotropes at which enteral feed is well tolerated.
View Article and Find Full Text PDFCombined low-dose dobutamine and exercise stress echocardiography: a new hybrid protocol to detect inducible ischaemia.
Eur Heart J Imaging Methods Pract
January 2024
Department of Echocardiography, Harefield Hospital, Royal Brompton and Harefield Hospitals (part of Guy's and St Thomas' NHS Foundation Trust), Hill End Rd, Harefield, Uxbridge UB9 6JH, UK.
Aims: Myocardial response to stress echocardiography may be elicited physiologically, through exercise, or pharmacologically, often with dobutamine. Both have advantages but also limitations due to reduced exercise capacity or side-effects to stressor agent/lack of closeness to true pathophysiology of ischaemic cascade. We have combined low-dose dobutamine and exercise, creating a 'hybrid' protocol to utilize the advantages of both techniques and limit the drawbacks.
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