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Understanding hepcidin for iron management in pregnancy.

Transfus Med

January 2025

SUWON (Surgery, Oncology and Womens), Department of Haematology, University of Oxford, Oxford, UK.

Iron deficiency anaemia (IDA) poses a significant health challenge during pregnancy, affecting up to 30% of pregnant women in the UK. It has been linked to poor health outcomes for the mother, foetus, and the infant. Despite its prevalence and impact, current diagnostic and therapeutic approaches are limited.

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Background/purpose: Revascularization procedures are used over apexification to treat teeth with necrotic pulp tissues and incomplete root formation. Clinically, inducing proliferation, migration, matrix deposition, and differentiation of stem cells from apical papilla (SCAPs) are critical for pulp regeneration. The study aimed to elucidate the impact of bone morphogenetic protein-4 (BMP-4) on plasminogen activation molecules and the osteogenic/odontogenic differentiation of SCAPs, as well as understand the related signaling mechanisms.

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Cardiovascular diseases cause significant morbidity and mortality worldwide. Engineered cardiac organoids are being developed and used to replicate cardiac tissues supporting cardiac morphogenesis and development. These organoids have applications in drug screening, cardiac disease models and regenerative medicine.

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The correlation of region-specific lifestyle and subjective perception of oral health with oral health-related quality of life among Tibetan early adolescents in Ganzi: a cross-sectional study.

PeerJ

January 2025

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Background: The oral health-related quality of life (OHRQoL) of Tibetan adolescents has been largely overlooked.

Aim: This cross-sectional study examined the association of region-specific lifestyle, subjective perception, and clinician conditions of oral health with Tibetan adolescents' OHRQoL in Ganzi, Sichuan.

Methods: The OHRQoL was measured using standardized Child Oral Impacts on Daily Performances (sC-OIDP) scores.

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"It's Like You're Feeding Your Child Twice": Barriers and Facilitators to Human Milk Feeding Children With Cystic Fibrosis.

Pediatr Pulmonol

January 2025

Department of Pediatrics, Division of Pulmonary, Allergy/Immunology, Cystic Fibrosis and Sleep, Emory University, Atlanta, Georgia, USA.

Background: Cystic Fibrosis Foundation guidelines recommend human milk (HM) as the ideal source of nutrition for children with CF (cwCF). Despite known pulmonary and nutritional benefits, fewer cwCF ever receive HM compared to the general population. Early nutrition choices are preference-sensitive, yet little is known about the factors that impede or sustain HM feeding among parents of cwCF.

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